脾多肽注射液对脑卒中合并肺感染患者疗效及对血清中IL-18和IL-35的影响被引量：3

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摘要目的观察注射用脾多肽注射液对脑卒中合并肺感染患者的治疗效果及对血清中白细胞介素(IL)-18和IL-35水平的影响。方法脑卒中合并肺感染患者126例随机分为观察组、对照组各63例。对照组在常规治疗脑卒中的同时依据药敏培养结果加用抗生素。观察组在对照组治疗基础上加用脾多肽注射液。于治疗前、后检测血清中IL-18和IL-35的表达。结果治疗10 d后,观察组总有效率明显高于对照组。观察组治疗后血清中IL-18的表达下降值、IL-35的表达升高值明显高于对照组。结论注射用脾多肽注射液对脑卒中合并肺感染的治疗效果理想,同时能有效地下调血清中IL-18的表达,上调血清中IL-35的表达,优化内环境。

作者李万春赖学章孟晏莉

机构地区驻马店市中心医院神经内科

出处《中国老年学杂志》 CAS CSCD 北大核心 2015年第16期4531-4532,共2页 Chinese Journal of Gerontology

关键词注射用脾多肽注射液脑卒中肺感染白细胞介素(IL)-18 IL-35

分类号 R743.3 [医药卫生—神经病学与精神病学] R563 [医药卫生—呼吸系统]

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