老年人群呼吸道感染病原体IgM检测结果

Detection of IgM of pathogens causing respiratory tract infection in elderly people

目的了解本院老年人群呼吸道感染病原体的流行病学特点,为指导临床诊断和治疗、制定预防措施提供依据。方法借助呼吸道感染病原体Ig M试剂,采用间接免疫荧光技术同时检测呼吸道感染患者9种病原体:肺炎支原体(MP)、乙型流感病毒(INFB)、副流感病毒(PIVs)、嗜肺军团菌(LP)、呼吸道合胞病毒(RSV)、甲型流感病毒(INFA)、肺炎衣原体(CP)、腺病毒(ADV)以及Q热立克次体(COX)观察其季节性变化。结果 1 063例老年人群中共检出阳性259例,阳性率为24.34%。老年人群呼吸道感染的主要病原体为MP、INFB、PIVs、LP与RSV。MP的感染率最高,为15.90%;而INFB感染存在季节性差异(P<0.05)。3.5%的阳性患者发生了混合感染,主要混合感染类型为MP与INFB。结论 MP为老年人群呼吸道感染的主要病原体。老年人群呼吸道感染应重点关注MP的诊断与防治,并在INFB高发季节注意混合感染。

Objective To explore the epidemiology of respiratory tract pathogens in elderly people. Methods Serum samples of elderly people with respiratory tract infection were tested with the Pneumoslide Ig M kit. The Pneumoslide Ig M technology could simultaneously diagnose 9 main viral and atypical pathogens: Mycoplasma pneumoniae( MP),Influenza B( INFB),Parainfluenza 1,2 and 3( PIVs),Legionella pneumophilaserogroup 1( LP1),Respiratory syncytial virus( RSV),Influenza A( INFA),Chlamydophila pneumonia( CP),Adenovirus( ADV),Coxiellaburnetii( COX). Results 1 063 serum specimens tested 259 positive. MP was the dominant pathogen with the positive rate of 15. 90%,the pathogens ranking the second place to the fifth place were INFB,PIVs,LP1,and RSV,the positive rates were 2. 92%,2. 35%,1. 6%,and 1. 41%,respectively. INFB infecction was associated with season( P < 0. 05). 3. 5% of positive patients suffered from mixed infection,especially MPand Influenza B. Conclusions MP is the dominant pathogen of respiratory tract infection in elderly people.More attentions are paid to diagnosis and treatment of MP,and the mixed infection during peaking season of INFB.