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高脂血症动物模型研究进展 被引量：9

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摘要 高脂血症是指脂肪代谢或转运异常所致的血浆中1种或多种脂质高于正常的疾病,其临床发病率高,常分为高胆固醇(TC)血症、高甘油三脂(TG)血症和混合型高脂血症(即同时表现高TG和高TC血症)〔1〕,是导致多种重大疾病如心脑血管病、肥胖和严重糖尿病等的重要危险因素。高脂血症动物模型的建立对于高脂血症发病机制及相关药物的筛选研究具有重要意义。已建立的模型大致可分为饮食诱导、
作者 王颖 于学慧
机构地区 山东大学药学院 山东大学实验动物中心
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第19期5654-5657,共4页 Chinese Journal of Gerontology
基金 山东省优秀中青年科学家科研奖励基金(No.BS2010SW018)
关键词 高脂血症 动物模型 转基因
分类号 R589.2 [医药卫生—内分泌] R [医药卫生]
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参考文献14

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  • 2Katie M.Lebold,Kathleen A.Grant,Willard M.Freeman,Kristine M.Wiren,Galen W.Miller,CaitlinKiley,Scott W.Leonard,Maret G.Traber.Individual Differences in Hyperlipidemia and Vitamin E Status in Response to Chronic Alcohol Self‐Administration in Cynomolgus Monkeys[J]. Alcoholism: Clinical and Experimental Research . 2011 (3)
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共引文献1

同被引文献104

引证文献9

二级引证文献49

中国老年学杂志
2015年 第19期

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