2004~2013年中药复方口服治疗溃疡性结肠炎的文献分析

Document analysis of composing oral Chinese medicine prescriptions treating ulcerative colitis from 2004 to 2013

目的分析中药复方口服治疗溃疡性结肠炎(UC)的文献研究现状。方法检索中国知网(CNKI)数据库中2004~2013年12月中药复方口服治疗UC的文献,录入Note Express2.9软件,分析文献类型、研究类型、年份、期刊、中药使用频次、证型等相关研究现状。结果共纳入文献374篇,文献类型中,期刊文章最多占90.64%,其次为学位论文占6.15%;半随机对照试验最多占53.4%,其次为非随机对照试验占34.4%;2011年份最多占13.9%,其次为2008年占11.2%;陕西中医刊出的文献最多占5.0%,其次为中医内科杂志占3.7%;使用频次最高的中药为黄连,其次为白术、甘草、白芍、茯苓、党参、木香、当归、陈皮;湿热内蕴证最多占31.25%,其次为脾胃虚弱证占17.5%。结论中药复方口服治疗UC仍是临床研究的热点,多应用健脾祛湿、温肾止泻、理气活血、平调寒热之法,因而补益类、清热类、温里类、理气类药物应用较多。

Objective To analyze the document research status of composing oral Chinese medicine prescriptions for ulcerative coli-tis ( UC) and to provide some reference for clinical treatment.Methods The clinical literatures on the treatment of UC with oral Chinese medicine prescriptions were collected from 2004 to December 2013 by CNKI.The situation including the document type, research type, age, magazine,thedrugfrequencyintheprescriptionsandthetraditionalChinesemedicinesyndromeetcwereanalyzed.Results 374articles were internalized, which mostly included periodicals(90.64%), followed by dissertations (6.15%); which mostly included semi-random control trials(53.4%) followed by non-random control trials(34.4%),which mostly magazines (13.9%) on 2011 followed by 2008(11. 2%),which mostly included<Shaanxi J Tradit Chin Med>(5.0%), followed by <Internal Medicine of Traditional Chinese Medicine>(3. 7%).Coptis was the highest frequency of traditional Chinese medicine than Atractylodes, Licorice, Radix Paeoniae , Alba,Poria cocos, Codonopsis pilosula, Aucklandiae,Angelica sinensis, Citrus reticulate, which mostly included endoretention of damp heat count in 31.3%, followed by hypofunction of the spleen and stomach count in 17.5%.Conclusions The hot research area is always that composing oral Chi-nese medicine prescriptions for UC, applying the method on invigorating the spleen and eliminating dampness, warming the kidney and antid-iarrhea, supplementing qi and activating blood circulation as well as adjusting cold and heat, so the medicines belong to the tonic, the clear-ing heat, the warming internal and the regulating qi.