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3D-ASL与DSC-PWI在短暂性脑缺血患者中的应用 被引量:8

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摘要 目的对比研究动脉质子自旋标记(ASL)与动态磁敏感对比增强灌注成像(DSC-PWI)在评价短暂性脑缺血(TIA)患者脑部微循环中的应用。方法在DWI正常而短暂性脑缺血发作患者23例,均采用GE 3.0T MR行头部ASL和DSC-PWI检查,定性观察两种技术在TIA中的灌注表现。而在DSC-PWI中,分别CBF、CBV、MTT及TTP与ASL行阳性率对比,观察PWI中各项指标与ASL的CBF相关性。结果 23例患者中,ASL显示灌注不足18例,灌注过度2例,灌注正常3例;DSC-PWI显示灌注不足16例,灌注过度2例,灌注正常5例;两种方法结果一致15例,符合率为65.2%。而在DSC-PWI中,与CBF、CBV相比,ASL具有统计学差异(P<0.05);与MTT,TTP阳性率无明显统计学差异(P>0.05),但阳性率偏高。结论无创性ASL在检测TIA脑血流量灌注异常时与DSC-PWI具有同样的效果,敏感性偏高。
机构地区 吉林省人民医院
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第22期6374-6376,共3页 Chinese Journal of Gerontology
基金 吉林省卫生科研计划基金资助项目(20132061)
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