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非侵袭性远端肢体缺血后适应对急性脑梗死患者神经功能的恢复及生化指标变化的影响 被引量:2

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摘要 目的探讨非侵袭性远端肢体缺血后适应(NDLIP)对治疗急性脑梗死患者神经恢复作用及相关炎性因子的影响。方法选择2013年4月至2014年10月该院神经内科收治的急性脑梗死患者286例,采用随机数字法分为研究组(150例)和对照组(136例);对照组给予常规内科治疗,研究组在对照组的基础上给予NDLIP干预。采用美国国立卫生研究院的神经功能评分量表(NIHSS)评价入院时及入院治疗14 d后的神经功能,同时测量所有患者C-反应蛋白(CRP)、纤维蛋白原(FIB)及D-二聚体(D-D)水平。结果研究组治疗14 d后NIHSS评分较入院时显著下降(P<0.05),对照组无显著变化(P>0.05),且研究组NIHSS评分显著低于对照组(P<0.05);研究组治疗14 d后CRP、FIB及D-D水平较入院时均出现显著下降(P<0.05),对照组下降不明显(P>0.05),且研究组均显著低于对照组(P<0.05)。结论 NDLIP治疗急性脑梗死患者的疗效明显,能够促进患者神经功能的恢复,降低机体CRP、FIB及D-D水平,安全性高。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第22期6401-6403,共3页 Chinese Journal of Gerontology
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