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心肾综合征的生物标志物研究进展 被引量:8

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摘要 心脏和肾脏之间存在密切联系,当其中一个器官功能损害时会影响另一个器官功能,目前被定义为心肾综合征(CRS)[1]。心功能不全时通过心输出量的下降、肾素-血管紧张素-醛固酮系统(RAAS)的激活、中心静脉压的升高等导致肾损害,如肾灌注下降、肾血管阻力增加、肾瘀血,从而出现肌酐升高、蛋白尿、肾小球滤过率(GFR)下降等;反之,肾功能不全时因RAAS激活、高钾血症、钠水潴留留等导致心肌劳损.
作者 陈霞 苏鹏宇
出处 《中国老年学杂志》 CAS 北大核心 2019年第3期764-767,共4页 Chinese Journal of Gerontology
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