肠缺血再灌注损伤中钙超载的研究进展

Progress of calcium overload in intestinal ischemia reperfusion injury

在临床上,各种原因的病理性打击常引起肠道的缺血,而肠缺血再灌注损伤是其常见的病理变化。经相关研究证实肠缺血再灌注损伤在全身性的细菌感染、多器官功能障碍、休克等严重疾病及其进展过程中起着重要作用。而钙超载在肠缺血再灌注损伤的发生、发展中占据重要地位,通过总结、研究钙超载在肠缺血再灌注损伤中的机制及相关作用,可以进行相应的应对措施,从而减少肠缺血中的再灌注损伤,为临床工作提供理论支持,现本文就肠缺血再灌注损伤中钙超载的研究进展作一综述。

In clinical practice, the pathological changes of intestinal ischemia are usually caused by various causes, and intestinal ischemia-reperfusion injury is the common pathological changes. The related research have confirmed that intestinal ischemia reperfusion injury plays an important role in systemic bacterial infection, multiple organ dysfunction, shock and other serious diseases and its development process. Calcium overload occupies an important position in the occurrence and development of intestinal ischemia reperfusion injury, through summing and researching the mechanism and related function of calcium overload in intestinal ischemia reperfusion injury can reduce intestinal ischemia reperfusion injury by using corresponding measures and to provide theoretical support for clinical work. This paper reviewed the progress of calcium overload in intestinal ischemia reperfusion injury.