乳腺癌循环肿瘤细胞的临床应用进展

Clinical application advances of circulating tumor cells in breast cancer

循环肿瘤细胞可能在肿瘤发生的早期侵入血液循环系统中,并在恶性肿瘤转移过程中发挥着重要作用,本文将从乳腺癌循环肿瘤细胞的富集和检测技术在临床中的应用,以及循环肿瘤细胞的遗传和分子特征进行探讨,为患者的个体化治疗提供重要依据。

Circulating tumor cells(CTCs) may invade the blood circulation in the early stage of tumor, and play an important role in the metastasis process. This article mainly discussed the genetic and molecular mechanisms of CTCs and the clinical application about the CTCs enrichment and testing, which would provide important strategies for breast cancer patients as part of individual therapy.