抗凝药师参与3例华法林相关颅内出血的药学实践

Anticoagulant pharmacists participated in the pharmaceutical care of 3 patients with warfarin-related intracranial hemorrhage

通过抗凝药师参与会诊的3例华法林相关颅内出血病例,从患者的病理状态、基因多态性、药物相互作用等方面分析华法林所致颅内出血的原因,以及出血后的处理措施、重启抗凝的时机及重启抗凝方案的制订等,为患者制订个体化的治疗方案,并进行药学监护及随访,探讨抗凝药师参与华法林相关颅内出血患者的药物治疗及开展药学监护的方法,为治疗和预防华法林相关颅内出血提供参考。

Three patients with warfarin-related intracranial hemorrhage were consulted by anticoagulant pharmacists,and analysis was made on the reasons of warfarin causing intracranial hemorrhage concerning patients’pathological state,gene polymorphism and drug interactions.Treatment measures after the bleeding,the timing and formulation of re-starting anticoagulation,relevant and personalized therapeutic schemes were set up for the patients,and pharmaceutical care and follow-up visit were also conducted.Anticoagulant pharmacists participated in the drug therapy and pharmaceutical care of patients with intracranial hemorrhage caused by warfarin,provided reference for treating the patients with warfarin-related intracranial hemorrhage.