摘要
背景与目的:食管癌手术标本在切除后和甲醛固定后会发生收缩,但对其收缩规律进行研究的报道较少。本研究拟观察离体食管癌手术标本在切除后和甲醛固定后的收缩规律。方法:对我院手术切除的70例食管鳞癌标本,术中在食管切除前,用直尺测量肿瘤长度、上切端长度和下切端长度;当食管癌手术标本切除离体后立即在肿瘤对面沿食管纵轴剖开,在无牵拉情况下,测量上述指标;用10%甲醛固定上述标本48h后,再测量上述指标。结果:离体后食管癌手术标本与其体内实际长度的比率分别为:上切缘(40.71±10.02)%,肿瘤(83.59±16.57)%,下切缘(58.41±12.03)%;用10%甲醛固定48h后,食管癌手术标本与其体内实际长度的比率分别为:上切缘(40.06±10.50)%,肿瘤(80.92±15.88)%,下切缘(54.83±11.29)%。食管癌手术标本的上切缘长度,下切缘长度与肿瘤长度,在切除后及甲醛固定后与其体内实际长度相比较差异有显著性(P<0.05)。结论:食管癌手术标本在切除后及甲醛固定后与其体内实际长度相比有显著的收缩。
BACKGROUND &OBJECTIVE:There are some kinds of shrinkage in resected specimens of esophageal carcinoma;however,there were few reports on its regularity.This study was designed to investigate the degree of shrinkage in resected specimens of esophageal carcinoma. METHODS:Specimens of seventy patients with esophageal squamous cell carcinoma who underwent resections in Cancer Center,Sun Yat Sen University were collected.The length of the upper margin,the tumor,and the lower margin were measured with a ruler during operation before the esophagus was removed (in situ). After the esophagus was removed, the specimens were cut longitudinally on the side opposite the tumor, then the length of the upper margin, the tumor, and the lower margin were measured again without retraction. After 48 h fixation of 10%formalin (fixed),the length of the upper margin,the tumor,and the lower margin were measured again. RESULTS: After resection,the shrinkage rates of the upper margin, the tumor,and the lower margin were (40.71±10.02)%,(83.59±16.57)%,and (58.41±12.03)%of their in situ length;after 48 h fixation of 10%formalin, the shrinkage rates of the upper margin,the tumor, and the lower margin were (40.06±10.50)%, (80.92±15.88)%, and (54.83±11.29)%of their in situ length (P< 0.05). CONCLUSION: The specimens of esophageal carcinoma shrink remarkably after removed and after formalin fixation.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
2004年第2期193-195,共3页
Chinese Journal of Cancer
关键词
食管癌
手术标本
长度收缩
甲醛固定
Esophageal carcinoma
Surgical operation
Resected specimens
Shrinkage