肥大细胞及其分泌活性物质与婴幼儿腮腺血管瘤关系的研究

Relationship between types of mast cells and its active granulae with infant hem angioma of parotid

目的 :研究肥大细胞及其分泌活性物质与腮腺血管瘤的关系。方法 :采用特殊肥大细胞染色方法和图象分析技术 ,对 40例腮腺血管瘤、5例正常腮腺组织中的肥大细胞进行定性和定量分析。结果 :腮腺血管瘤以含肝素的结缔组织型肥大细胞为主。结论

Objective: To investigate the relationship between the ac tive granulae in mast cells and infant hemangiomas of parotid gland. Methods: Surgical samples of parotid gland hemangioma were obtained from 40 infants under the age of 6 months and those of normal parotid gland tis sue from 5.The samples were investigated by safranin staining,alcian blue and th ionine staining, and image analysis technique. Results: Th e percentage of thionine positive cells vs tissue area in hemangioma and normal parotid gland tissue was 1.132±0.195 and 0.335±0.122 ( P <0.01),the grey le vel was 86.100±3.241 and 81.167±4.442 ( P <0.01);that of alcian blue and sa franin positive cells in the two groups were 1.461±0.546 and 0.658±0.239( P <0.01).the grey level was 101.600±6.420 and 86.933±7.153( P <0.01),respectiv ely.Conclusion: In infant hemangioma tisse of parotid gla nd the majority tissue type is connective countainning heparin positive mast cel ls.There is a close relationship between types of mast cells and its active gran ulae with infant hemangioma of parotid gland.