摘要
紫丹参为彝族、苗族等少数民族民间常用药物,应用广泛,但其药用历史及本草考证资料有限。该文通过系统查阅历代本草文献,结合我国几种鼠尾草属植物的形态描述和野外实地调查,对民族药紫丹参的基原、名称、药用历史、功能主治、民间应用、药理作用等进行了系统考证和整理,以期为紫丹参资源合理利用和开发提供科学依据。研究认为古代本草记载的紫丹参与今用紫丹参物种一致,为云南鼠尾草Salvia yunnanensis的根,其药用历史约600年,具有广泛的民间临床应用基础。主要用于经闭、痛经、月经不调、跌打肿痛、肢体麻木及多种血瘀证。紫丹参的相关临床应用与与现代药理学证据是相互支撑的,表明基于临床经验总结的传统医学具有较高的挖掘价值。基于本草文献考证的证据表明,紫丹参在妇科、血瘀等领域具有较高的研究开发价值,应充分挖掘紫丹参的民间临床应用经验,在此基础上,进一步加强其物质基础、药效、作用机制等相关研究,促进紫丹参的资源利用和产品开发,使其更好服务于人类。
By consulting literatures of traditional Chinese medicine(TCM),comparing data about the morphological description of several species from genus of Salvia,and combining the biological studies in resources,this paper made a textual research for the origin,name,medicinal history,functional dominance and folk application Salviae Yunnanensis Radix.This study aimed to provide a reference for further studies and utilization of Salviae Yunnanensis Radix.The findings revealed that the origin of Zidanshen recorded in ancient Chinese herbal literatures was S.yunnanensis,which were widely used for amenorrhea,dysmenorrhea,irregular menstruation,tumescent pain,limb numbness and many kinds of blood stasis.Relevant clinical application and modern pharmacological evidences of Salviae Yunnanensis Radix are mutually supportive,which indicates that TCM based on clinical experience has a high development value.The herbal literatures revealed that Salviae Yunnanensia Radix has a high research and development value in gynecology,blood stasis and other fields.We shall fully excavate folk experience in clinical application of Salviae Yunnanensis Radix.On this basis,we shall further strengthen relevant researches on material basis,pharmacodynamics and mechanism,in order to promote the utilization of resources and product development of Salviae Yunnanensis Radix.
作者
段宝忠
李巍
邓海星
兰竹慧
吴中相
罗晓芳
Leslaw Mleczko
DUAN Bao-zhong;LI Wei;DENG Hai-xing;LAN Zhu-hui;WU Zhong-xiang;LUO Xiao-fang;Leslaw Mleczko(College of Pharmaceutical and Chemistry,Dali University,Dali 671000,China;Bayer Healthcare Co.Ltd.,Shanghai 200127,China;Dianhong Pharmaceutical Group Co.Ltd.,Kunming 650000,China;Bayer(China)Limited,Shanghai 200127,China;Bayer AG,Leverkusen 51368,Germany)
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2019年第15期1-7,共7页
Chinese Journal of Experimental Traditional Medical Formulae
基金
大理大学-滇虹药业合作项目(CDDC2017087)
大理大学博士启动基金项目(KYBS201737)
大理大学中药资源与民族药创新团队项目(ZKLX2019318)
云南省中青年学术技术带头人和后备人才项目(2015HB058)
国家自然科学基金项目(31460084)
关键词
民族药
紫丹参
本草考证
血瘀
ethnic medicine
Salvia yunnanensis
herbal textual research
blood stasis