超微血管成像技术检测颈动脉斑块内新生血管预测脑梗死发生的价值

Value of superb microvascular imaging in detecting neovascularization in carotid plaque in predicting cerebral infarction

目的探讨超微血管成像(SMI)技术检测颈动脉斑块内新生血管预测脑梗死发生的诊断价值。方法 150例颈动脉斑块患者,均使用SMI技术进行检测,根据斑块内新生血管分布进行SMI分级,与CT结果比较(证实有无脑梗死),分析颈动脉斑块SMI分级与脑梗死发病率之间的关系。结果 150例入选者斑块SMI分级:0级17例, CT证实有脑梗死者8例,无脑梗死者9例;Ⅰ级40例,CT证实有脑梗死者24例,无脑梗死者16例;Ⅱ级93例, CT证实有脑梗死者92例,无脑梗死者1例。随着SMI分级的增加, CT阳性检出率呈上升趋势,差异具有统计学意义(P<0.01)。SMI分级与CT的相关性分析结果显示, SMI分级与CT结果呈正相关(r=0.516, P<0.01)。结论利用SMI技术对斑块内新生血管进行检测分析,可预测脑梗死的发生风险。

Objective To discuss the diagnostic value of superb microvascular imaging(SMI) technique in detecting neovascularization in carotid plaque in predicting cerebral infarction. Methods A total of 150 cases of carotid plaque patients were detected by SMI technique. According to the distribution of neovascularization in the plaque, SMI grading was performed and compared with CT results(confirming the presence of cerebral infarction). The relationship between SMI grading of carotid plaque and the incidence of cerebral infarction was analyzed. Results SMI grade of 150 plaques: 17 cases of grade 0, including 8 cases of cerebral infarction confirmed by CT and 9 cases of non-cerebral infarction;40 cases of grade I, including 24 cases of cerebral infarction confirmed by CT, 16 cases of non-cerebral infarction;93 cases of grade II, including 92 cases of cerebral infarction confirmed by CT and 1 case of non-cerebral infarction. With the increase of SMI grade, the positive detection rate of CT showed an upward trend, and the difference was statistically significant(P<0.01). Correlation analysis between SMI grade and CT showed that SMI grade was positively correlated with CT results(r=0.516, P<0.01). Conclusion Detection and analysis of neovascularization in plaque by SMI technique can predict the risk of cerebral infarction.