阿米卡星联合糜蛋白酶辅助治疗剖宫产术后腹部切口脂肪液化的效果评价

Evaluation of the effect of amikacin combined with chymotrypsin in the adjuvant treatment of fat liquefaction in abdominal incision after cesarean section

目的探讨阿米卡星联合糜蛋白酶辅助治疗剖宫产术后腹部切口脂肪液化的效果。方法 73例剖宫产术后腹部切口脂肪液化患者,依照治疗方式的差别将其分为对照组(36例)与试验组(37例)。对照组施以常规消毒换药联合远红外灯照射治疗,试验组在对照组基础上施以阿米卡星联合糜蛋白酶辅助治疗。比较两组患者的临床治疗效果、腹部切口拆线时间、住院时间、切口愈合时间、切口愈合情况与患者的治疗满意度。结果试验组的临床治疗总有效率为94.59%,明显高于对照组的55.56%,差异具有统计学意义(P<0.05)。试验组患者的腹部切口拆线时间、住院时间、切口愈合时间分别为(7.26±0.82)、(10.69±1.73)、(3.31±1.48)d,均短于对照组的(8.87±1.36)、(13.52±2.54)、(9.54±1.67)d,差异均具有统计学意义(P<0.05)。试验组切口愈合良好率为97.30%,高于对照组的63.89%,差异具有统计学意义(P<0.05)。试验组患者的治疗满意度为97.30%,高于对照组的58.33%,差异具有统计学意义(P<0.05)。结论阿米卡星联合糜蛋白酶辅助治疗剖宫产术后腹部切口脂肪液化具有显著的临床效果,不仅能够有效的提升患者的临床治疗效果,同时能够有效的缩短腹部切口拆线时间、住院时间与切口愈合时间,具有较高的临床推广价值。

Objective To discuss the effect of amikacin combined with chymotrypsin in the adjuvant treatment of fat liquefaction in abdominal incision after cesarean section.Methods A total of 73 patients with fat liquefaction in abdominal incision after cesarean section were divided by different treatment methods into control group(36 cases)and experimental group(37 cases).The control group was treated with conventional disinfection and dressing change combined with far-infrared lamp irradiation treatment,and the experimental group was treated with amikacin and chymotrypsin on the basis of the control group.Comparison were made on clinical treatment effect,abdominal incision suture removal time,hospitalization time,incision healing time,incision healing and patient satisfaction satisfaction between the two groups.Results The experimental group had obviously higher total effective rate of clinical treatment as 94.59%than 55.56%in the control group,and the difference was statistically significant(P<0.05).The experimental group had shorter abdominal incision suture removal time,hospitalization time,incision healing time respectively as(7.26±0.82),(10.69±1.73)and(3.31±1.48)d than(8.87±1.36),(13.52±2.54)and(9.54±1.67)d in the control group,and the difference was statistically significant(P<0.05).The experimental group had higher incision healing good rate as 97.30%than 63.89%in the control group,and the difference was statistically significant(P<0.05).The experimental gorup had higher treatment satisfaction as 97.30%than 58.33%in the control group,and the difference was statistically significant(P<0.05).Conclusion Combination of amikacin and chymotrypsin shows significant clinical effect in the adjuvant treatment of abdominal incision fat liquefaction after cesarean section.It can not only effectively improve the clinical efficacy of patients,but also effectively shorten abdominal incision suture removal time,hospitalization time and wound healing time.It has high clinical promotion value.