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高级动态血流成像技术评估阿托伐他汀对颈动脉斑块新生血管的作用及对脑梗死的预防价值

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摘要 目的针对颈动脉斑块新生血管采用高级动态血流成像技术(ADF)评估阿托伐他汀对其的作用及对脑梗死的预防价值。方法 180例颈动脉斑块患者,通过ADF检测筛出72例斑块内有新生血管患者,随机分为对照组和治疗组,每组36例。对照组采用常规药物治疗,治疗组采用阿托伐他汀治疗。分析患者斑块中血流显示情况,根据高级动态血流成像中颈动脉斑块内有无血流分组比较脑梗死发生情况,并比较两组肝功能异常情况。结果 72例患者不同回声斑块中血流显示情况:中等回声斑块6例,混合回声斑块9例,低回声斑块10例,强回声斑块5例。72例患者根据ADF中颈动脉斑块内有无血流分为有血流组(30例)和无血流组(42例),患者均接受CT或磁共振成像(MRI)检查:有血流组患者发生脑梗死22例(73.33%),无血流组患者发生脑梗死20例(47.62%),有血流组患者的脑梗死发生率高于无血流组,差异有统计学意义(P<0.05)。治疗组患者肝功能异常10例(27.78%),肝功能正常26例(72.22%);对照组患者肝功能异常13例(36.11%),肝功能正常23例(63.89%);两组肝功能异常发生率比较差异无统计学意义(P>0.05)。结论运用ADF检测斑块内有新生血管患者,能显著降低患者的血脂水平和颈动脉硬化的速度,对预防脑梗死的发生,具有临床价值。
出处 《中国实用医药》 2019年第18期78-80,共3页 China Practical Medicine
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