不同麻醉方法在犬剖腹产手术的临床效果

The effect of different anesthesia methods on caesarean section of pregnant dog

为探究不同麻醉方法对犬剖腹产手术的应激效果及仔犬的生活容态。本试验采用846合剂全身麻醉、普鲁卡因硬膜外腔麻醉及846合剂与普鲁卡因联合麻醉对怀孕期满的犬进行剖腹产手术,在剖腹产手术的麻醉前(T1)、切开腹壁(T2)、手术30min(T3)、手术完(T4)、术后24h(T5)、术后48h(T6)进行静脉采血,检测血浆皮质酮和血糖含量,比较术后幼犬平均日增重及生活容态。结果表明:846麻醉组和硬膜外麻醉组血浆皮质醇质量浓度在T2~6这5个时期显著高于自然分娩组和联合麻醉组(P<0.05),联合麻醉组仅在T3时血浆皮质醇质量浓度显著高于自然分娩组(P<0.05);846麻醉组和硬膜外麻醉组血糖质量浓度在T2~6时期均显著高于自然分娩组及联合麻醉组(P<0.05),联合麻醉组仅在T3~4时期显著高于自然分娩组(P<0.05);联合麻醉组中的幼犬增重、生活容态与自然分娩时幼犬最接近,846麻醉组效果较差,硬膜外麻醉组效果最差。本研究证明846合剂与普鲁卡因硬膜外腔联合麻醉方法能够更有效缓解犬剖腹产手术的应激反应。

The caesarean stress effects and living conditions of different anesthesia methods were investigated in pregnant dog.846 mixture general anesthesia,epidural anesthesia and combined anesthesia by 846 and procaine were used in caesarean dogs.Blood samples were taken at pre-anesthesia(T1),immediately after opening abdomen(T2),30 min post the operation(T3),at the end of operation(T4),24h(T5)and 48h(T6)after the operation,respectively.The average level of plasma cortiso and blood sugar were measured by radioimmunoassay and colorimetric assay,respectively.The results showed that the concentrations of plasma cortisol at T2~6time in 846 anesthesia group and epidural anesthesia group were significantly higher than that of control group and combined anesthesia group(P<0.05).Compared with control group,there was significant higher at T3 time in the combined anesthesia group(P<0.05);(2)The concentrations of blood sugar at T2-6time in 846 anesthesia group and epidural anesthesia group was significantly higher than that control group and combined anesthesia group(P<0.05).Compared with control group,there was significant increase in the combined anesthesia group at T3-4time(P<0.05);The weight and living conditions of puppies in combined anesthesia group were similar to the control group,effects in the 846 anesthesia is poor,the worst effect was the epidural anesthesia group.It is concluded that the combined anesthesia group can effectively relieved stress response in caesarean section of dogs.