老年性肺炎患者血浆NO、转化生长因子-β_1、ET水平联合检测的临床意义

Measurement of NO,TGF-β_1 and ET in plasma from aged patients with pneumonia and its clinical significance

目的 探讨老年性肺炎患者血浆 NO、转化生长因子 -β1 和 ET含量的变化。方法 分别应用酶法和放射免疫分析法测定了 36例老年性肺炎患者血浆 NO、转化生长因子 -β1 和 ET水平 ,并与 30名正常健康人作对照。结果 老年性肺炎患者血浆中 NO、ET、转化生长因子水平高于正常人 (P<0 .0 5～ 0 .0 1 )。结论 老年肺炎患者血浆中NO、转化生长因子 -β1 、ET水平与疾病的发生和发展有密切的关系 。

Objective To explore the changes of plasma NO,TGF β 1 and ET in aged patients with pneumonia.Methods NO was detected by EIA,TGF β 1 were detected by RIA and TGF β 1 were detected by RIA in 36 aged patients with pneumonia and 30 normal controls.Results The levels of NO,TGF β 1 and ET were obviously higher than those in the normal controls( P <0.05～0.01).Conclusion Detection of plasma NO,TGF β 1 and ET levels,which are closely related to the development of pnemonia in aged patients,has important clinical values.