摘要
目的:研究妇科养荣胶囊对哺乳期大鼠泌乳作用的影响。方法:对生育后的雌性大鼠服用妇科养荣胶囊,每日测定仔鼠体重,以每窝仔鼠体重总和减去前一天体重总和为母鼠泌乳量,实验1周后,眼眶取血测定血清泌乳素(PRL)水平。结果:妇科养荣胶囊可显著增加仔鼠体重,中、高剂量组于第4、7、10、17、21日有统计学意义(p<0.01),低剂量组第10、14、17日有统计学意义(P<0.05);妇科养荣胶囊可显著增加母鼠乳汁分泌量,低剂量组于第19、20日,中剂量组于第6、7、19、20日,高剂量组于第7、15、19、20日有统计学意义(P<0.01);妇科养荣胶囊有升高血清PRL水平的趋势,但无统计学意义。结论:妇科养荣胶囊具有提高乳汁分泌和增强幼体发育的作用。
Objective To study the effect of Fukeyangrong capsule on the lactation of rats.Method The postnatal female rats were treated with Fukeyangrong capsule.The body weight of newborn rats is measured daily,and the lactation amount is calculated,which is determined by the difference of the sum body weight of newborn rats between the first day and the second day.One week later,the blood of female rats is collected from orbital veins,and the prolactin in serum is measured.Result Firstly,Fukeyangrong capsule can increase the body weight of newborn rats significantly,the BW of the newborn rats in the medium and high dose group is increased significantly in 4d,7d,10d,17d,21d(P<0.01),and the BW in low dose group is increased significantly in 10d,14d and 17d(P<0.05).Secondly,Fukeyangrong capsule can also enhance the milk secretion,the lactation of low dose group has increased significantly in 19d and 20d,the lactation of medium and high doses has increased significantly in 6d,7d,19d and 20d(P<0.01),the lactation in high dose group has increased significantly in 7d,15d,19d,20d(P<0.01).Thirdly,the Fuekyangrong capsule can increase the serum prolactin of postnatal female rats, but there is no statistical meaning.Conclusion Fukeyangrong capsule can increase the lactation of postnatal female rats and improve the growth of newborn rats.
