摘要
目的:探讨肺泡表面活性物质(PS)对新生儿持续肺动脉高压(PPHN)辅助治疗时的作用和疗效。方法:选取我院儿科34例PPHN患儿分为治疗组与对照组,治疗组给予PS联合机械通气治疗,治疗组单纯给予机械通气治疗。结果:8h后治疗组较对照组机械通气时间及氧合肺功能指标FiO2、PIP、OI等明显改善(P<0.05)结论:PS辅助机械通气可以显著降低PPHN患儿的肺动脉压力,改善预后。
Objective:To investigate the pulmonary surfactant(PS) of neonatal persistent pulmonary hypertension(PPHN) when the role of adjuvant therapy and treatment.Methods:34 cases of PPHN pediatric hospital were divided into treatment group and control group,treatment group received PS combined mechanical ventilation,the treatment group were given mechanical ventilation.Results:8h post-treatment group than the control group of mechanical ventilation and oxygenation in pulmonary function FiO2,PIP,OI,etc.improved significantly(P<0.05) Conclusion:PS assisted mechanical ventilation in children with PPHN can significantly reduce pulmonary artery pressure and improve prognosis.