摘要
为探讨不同人群中乙型肝炎病毒(HBV)感染标志的分布特点,我们对原发性肝癌病人、急性肝炎、慢性活动性旰炎住院病人,以及肝癌高发区和低发区一般人群用固相放射免疫。法(RIA)检测 HBV 感染标志。
HBV infection marker was tested by RIA and ELISA in 55 cases of primary hepatic cell carcinoma,105 cases of chronic active hepatitis,211 cases of acute hepatitis,1161 persons of the population at high risk of liver cancer and 822 persons of those at low risk of the cancer.It was found that the positive rate of HBsAg plus high titer of anti-HBc (RIA inhibition rate>80%) was highest in liver cancer cases (85.5%) and decre- ased successively in chronic hepatitis,acute hepatitis,population at high risk of liver carcinoma and those at low risk of the cancer.The positive rate of single anti-HBc aried in the opposite direction,being lowest in liver cancer patients. HBsAg plus high titer of anti-HBc could be considered as the marker of sustained hepatitis infection.Its positive rate was much higher in the population at high risk of liver cancer than those at low risk of the cancer.The high rate of sustained infection might be related to some promoting factors in the environment.
