期刊文献+

氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的疗效观察

下载PDF
导出
摘要 目的:分析氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的临床疗效,为临床治疗高血压合并冠心病提供可参考依据。方法:选取2017年2月至2018年2月来本院就诊的86例高血压合并冠心病患者作为研究对象,按照入院号的奇偶性随机分为对照组与观察组。对照组给予氨氯地平治疗,观察组给予氨氯地平阿托伐他汀钙片治疗。比较两组患者的临床效果、治疗前后血压、IMT水平变化情况。结果:两组患者治疗前的舒张压、收缩压以及IMT水平相比较差异无统计学意义(P> 0.05),治疗后,两组患者舒张压、收缩压以及IMT水平均降低,且观察组降低幅度明显大于对照组,差异具有统计学意义(P<0.05)。观察组无效8例,有效率为81.40%,对照组无效13例,有效率为69.77%,观察组有效率比对照组高,差异具有统计学意义(P<0.05)。结论:氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的临床疗效好,能在短时间内患者临床症状,显著降低血压,改善心绞痛症状。
作者 胡修魁
出处 《中外女性健康研究》 2019年第3期48-49,共2页 Women's Health Research
  • 相关文献

参考文献6

二级参考文献48

  • 1侯旭红,王新武.应用氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的临床疗效观察[J].当代医药论丛,2014,12(1):154-155. 被引量:106
  • 2Zhang X, Deguchi S, Deguchi K, et al. Amlodipine and atorvastatin exert protective and additive effects via antiapoptotic and antiau- tophagic mechanisms after transient middle cerebral artery occlusion in Zucker metabolic syndrome rats [J]. J Neurosci Res, 2011,89(8): 1228-1234.
  • 3Aalbers J. Amlodipine + atorvastatin single pill is the most effective choice for primary prevention[J]. Cardiovasc J Afr, 2010,21 (4):243.
  • 4Abrashkina ED, Shaalali N, Pakhrova OA, et al. Effect of atorvastatin on hemorheological parameters in patients with arterial hypertension with dyslipidemia[J]. Kardiologiia, 2010,50(5):25-28.
  • 5Kishi T, Sunagawa K. Combination therapy of atorvastatin and am- lodipine inhibits sympathetic nervous system activation and improves cognitive function in hypertensive rats [J]. Circ J, 2012,76 (8): 1934-1941.
  • 6Vinnik NI, Kutsenko LA, Kutsenko NL, et al. The effectiveness of pioglitazone in the treatment of patients with coronary heart disease on the background of metabolic syndrome[J]. Lik Sprava,2011,(3-4):71-78.
  • 7Hagita S, Osaka M, Shimokado K, et al. Combination of amlodipine and atorvastatin synergistically reduces leukocyte recruitment to me- chanically injured mouse femoral artery [J]. Hypertens Res, 2011, 34 (4):450-455.
  • 8Kawai H, Deguchi S, Deguchi K, et al. Synergistic benefit of combined amlodipine plus atorvastatin on neuronal damage after stroke in Zucker metabolic rat[J]. Brain Res, 2011,12; 1368:317-323.
  • 9Prajapati S, Desai CK, Dikshit RK. An evaluation of the effect of ator- vastatin on memory and psychomotor functions in hypertensive pa- tients[J]. J Postgrad Med, 2011,57(4):291-297.
  • 10Doyon M, Hale TM, Huot-Marchand JE, et al. Does atorvastatin induce aortic smooth muscle cell apoptosis in vivo?[J]. Vascul Phar- macol, 2011,54(1-2):5-12.

共引文献231

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部