摘要
卵巢上皮性癌是致死率最高的妇科恶性肿瘤,缺乏有效的早期诊断及筛查方法是预后差的主要原因,与卵巢上皮性癌的异质性及来源的多样性存在密切关系。传统的上皮性癌来源学说认为上皮性卵巢癌来自卵巢表面生发上皮,"第二苗勒管系统学说"对上述观点提出质疑,"二元论"学说彻底颠覆了传统的理论,但上述理论均存在局限性。近年来,卵巢上皮性癌多起源学说逐渐成为讨论热点。
Epithelial ovarian carcinoma has the highest fatality rate among gynecologic malignant tumors. Lacking of effective early diagnosis and screening method are the main reasons for its poor prognosis. There is a close relationship between the heterogeneity of epithelial ovarian carcinoma and the diversity of cancerous origins. According to the traditional theory,epithelial ovarian carcinoma derives from germinal epithelium at ovarian surface. The 'secondary Mullerian system ' theory has challenged above view. This'dualism'theory completely subverts the traditional one. However,both of the theories have their limitations. In recent years,the multiple origins theory of epithelial ovarian carcinoma has gradually become a hot point of discussion.
出处
《中国微创外科杂志》
CSCD
北大核心
2015年第12期1117-1120,共4页
Chinese Journal of Minimally Invasive Surgery
关键词
卵巢上皮性癌
输卵管来源
多起源学说
Epithelial ovarian carcinoma
Fallopian tube origin
Multiple origins theory
