天麻钩藤饮合清震汤治疗偏头痛48例临床观察

Clinical observation on gastrodia and uncaria decoction combined with Qingzhen Tang in treating 48 cases of Migraine

目的观察天麻钩藤饮合清震汤治疗偏头痛的临床疗效。方法将96例偏头痛患者随机分为治疗组和对照组各48例。治疗组用口服天麻钩藤饮合清震汤汤剂,对照组用口服盐酸氟桂利嗪胶囊,两组均治疗2周。2周后观察2组临床疗效。结果治疗组48例,男性10例,女性38例,年龄20~60岁,平均年龄(39.4±5.1)岁,病程最长10年,最短6个月,平均(4.7±2.5)年。对照组48例,男性9例,女性39例,年龄20~60岁,平均年龄(38.3±4.2)岁,病程最长10年,最短6个月,平均(3.8±2.1)年。两组临床资料比较差异无统计学意义(P>0.05),具有可比性。治疗组总有效率为95.83%;对照组总有效率为72.92%,两组比较差异有统计学意义(P <0.05)。治疗组48例患者,治疗过程中未见任何不良反应发生;对照组48例患者,其中出现瞌睡2例。患者均可耐受并能自行缓解,未中止治疗。通过一般体格检查项目,血常规、尿常规、大便常规、肝肾功能、心电图等观察,96例患者在服药期间均未发生明显变化,提示治疗组与对照组药物均无明显毒副作用。结论天麻钩藤饮合清震汤能有效改善偏头痛临床症状,临床疗效优于盐酸氟桂利嗪,值得临床推广应用。

Objective To observe the clinical effects of Gastrodia and Uncaria decoction combined with Qingzhen Tang in treating migraine.Methods 96 cases of migraine patients were randomly divided into two groups,48 patients in each group.The treatment group were given Gastrodia and Uncaria decoction combined with Qingzhen Tang,while the control group were given flunarizine hydrochloride capsules.The clinical effects were observed after the treatment of two weeks.Results Compared with the control group,the total effective rate of the treatment group was significantly higher,there was statistical significant difference between them(P <0.05).Conclusion Gastrodia and Uncaria decoction combined with Qingzhen Tang can improve the clinical symptoms of migraine.Compared with the control group it has better clinical effects and deserves further clinical applications.