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Trousseau's syndrome in a patient with advanced stage gastric cancer

Trousseau's syndrome in a patient with advanced stage gastric cancer
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摘要 Patients with cancer are at high risk for thrombotic events,which are known collectively as Trousseau's syndrome. Herein,we report a 66-year-old male patient who was diagnosed with terminal stage gastric cancer and liver metastasis and who had an initial clinical presentation of upper gastrointestinal bleeding. Acute ischemia of the left lower leg that resulted in gangrenous changes occurred during admission. Subsequent angiography of the left lower limb was then performed. This procedure revealed arterial thrombosis of the left common iliac artery with extension to the external iliac artery,the left common iliac artery,the posterior tibial artery,and the peroneal artery,which were occluded by thrombi. Aspiration of the thrombi demonstrated that these were not tumor thrombi. The interesting aspect of our case was that the disease it presented as arterial thrombotic events,which may correlate with gastric adenocarcinoma. In summary,we suggested that the unexplained thrombotic events might be one of the initial presentations of occult malignancy and that thromboprophylaxis should always be considered. Patients with cancer are at high risk for thrombotic events,which are known collectively as Trousseau’s syndrome. Herein,we report a 66-year-old male patient who was diagnosed with terminal stage gastric cancer and liver metastasis and who had an initial clinical presentation of upper gastrointestinal bleeding. Acute ischemia of the left lower leg that resulted in gangrenous changes occurred during admission. Subsequent angiography of the left lower limb was then performed. This procedure revealed arterial thrombosis of the left common iliac artery with extension to the external iliac artery,the left common iliac artery,the posterior tibial artery,and the peroneal artery,which were occluded by thrombi. Aspiration of the thrombi demonstrated that these were not tumor thrombi. The interesting aspect of our case was that the disease it presented as arterial thrombotic events,which may correlate with gastric adenocarcinoma. In summary,we suggested that the unexplained thrombotic events might be one of the initial presentations of occult malignancy and that thromboprophylaxis should always be considered.
出处 《World Journal of Gastroenterology》 SCIE CAS 2015年第34期10049-10053,共5页 世界胃肠病学杂志(英文版)
关键词 GASTRIC cancer ARTERIAL THROMBOTIC EVENTS Troussea Gastric cancer Arterial thrombotic events Troussea
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  • 1A. FALANGA,M. MARCHETTI,A. VIGNOLI.Coagulation and cancer: biological and clinical aspects[J]. Journal of Thrombosis and Haemostasis . 2013 (2)
  • 2Susan R Kahn,Wendy Lim,Andrew S Dunn.Prevention of VTE in nonsurgical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest . 2012
  • 3Timp JF,Braekkan SK,Versteeg HH,et al.Epidemiology of cancer-associated venous thrombosis. Blood . 2013
  • 4Varki Ajit.Trousseau’s syndrome: multiple definitions and multiple mechanisms. Blood . 2007
  • 5K. W. LEE,S. M. BANG,S. KIM,H. J. LEE,D. Y. SHIN,Y. KOH,Y. G. LEE,Y. CHA,Y. J. KIM,J. H. KIM,D. J. PARK,H. H. KIM,D. OH,J. S. LEE.The incidence, risk factors and prognostic implications of venous thromboembolism in patients with gastric cancer. Journal of Thrombosis and Haemostasis . 2010
  • 6Blom Jeanet W,Doggen Carine J M,Osanto Susanne,Rosendaal Frits R.Malignancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA : the journal of the American Medical Association . 2005
  • 7Lyman GH,Khorana AA,Kuderer NM,et al.Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer:American Society of Clinical Oncology Clinical Practice Guideline Update. Journal of Clinical Oncology . 2013

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