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Application of cystoscope in surgical treatment of hepatocellular carcinoma with portal vein tumor thrombus 被引量:6

Application of cystoscope in surgical treatment of hepatocellular carcinoma with portal vein tumor thrombus
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摘要 Development of portal vein tumor thrombus deteriorates the prognosis of hepatocellular carcinoma, while surgical treatment can offer a promising prognosis for selected patients. However, the possibility of residual lesions in portal vein after conventional thrombectomy is a main risk factor leading to postoperative recurrence. Therefore, ensuring the complete removal of tumor thrombus during operation is critical to improve prognosis. For the first time, we report here one case of hepatocellular carcinoma with portal vein tumor thrombus in which cystoscope was successfully applied as a substitute of intravascular endoscope to visualize the cavity of the portal vein. The patient was a 61-year-old man with a 7-cm tumor in the right lobe of the liver, with tumor thrombus invading the right branch and adjacent to the conjunction of the portal vein. After removal of the tumor, the Olympus CYF-VA2 cystoscope was used to check the portal vein from the opening stump of the right branch of the portal vein. In this case, residual thrombus tissue was found near the opening stump and the conjunction of the portal vein. The residual lesion was carefully retrieved from the stump after retraction of the cystoscope. The procedure was repeated until no residual lesion was found. The whole duration time of thrombectomy was 22.5(15 + 7.5) min. The patient was free from recurrence at 8 months after the procedure. Our work indicated that the cystoscope is a suitable substitute, with a proper size and function to check the portal vein system and ensure the curability of thrombectomy. Although welldesigned clinic trails are still needed, this procedure may further improve the postoperative prognosis of hepatocellular carcinoma with portal vein tumor thrombus. Development of portal vein tumor thrombus deteriorates the prognosis of hepatocellular carcinoma, while surgical treatment can offer a promising prognosis for selected patients. However, the possibility of residual lesions in portal vein after conventional thrombectomy is a main risk factor leading to postoperative recurrence. Therefore, ensuring the complete removal of tumor thrombus during operation is critical to improve prognosis. For the first time, we report here one case of hepatocellular carcinoma with portal vein tumor thrombus in which cystoscope was successfully applied as a substitute of intravascular endoscope to visualize the cavity of the portal vein. The patient was a 61-year-old man with a 7-cm tumor in the right lobe of the liver, with tumor thrombus invading the right branch and adjacent to the conjunction of the portal vein. After removal of the tumor, the Olympus CYF-VA2 cystoscope was used to check the portal vein from the opening stump of the right branch of the portal vein. In this case, residual thrombus tissue was found near the opening stump and the conjunction of the portal vein. The residual lesion was carefully retrieved from the stump after retraction of the cystoscope. The procedure was repeated until no residual lesion was found. The whole duration time of thrombectomy was 22.5 (15 + 7.5) min. The patient was free from recurrence at 8 months after the procedure. Our work indicated that the cystoscope is a suitable substitute, with a proper size and function to check the portal vein system and ensure the curability of thrombectomy. Although well-designed clinic trails are still needed, this procedure may further improve the postoperative prognosis of hepatocellular carcinoma with portal vein tumor thrombus.
出处 《World Journal of Gastroenterology》 SCIE CAS 2016年第22期5297-5300,共4页 世界胃肠病学杂志(英文版)
关键词 HEPATOCELLULAR carcinoma PORTAL VEIN tumor THROMBUS Surgical treatment THROMBECTOMY CYSTOSCOPE Hepatocellular carcinoma Portal vein tumor thrombus Surgical treatment Thrombectomy Cystoscope
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参考文献7

  • 1Yosuke Inoue,Kiyoshi Hasegawa,Takeaki Ishizawa,Taku Aoki,Keiji Sano,Yoshifumi Beck,Hiroshi Imamura,Yasuhiko Sugawara,Norihiro Kokudo,Masatoshi Makuuchi.??Is there any difference in survival according to the portal tumor thrombectomy method in patients with hepatocellular carcinoma?(J)Surgery . 2009 (1)
  • 2Iwao Ikai,Yuzo Yamamoto,Naritaka Yamamoto,Hiroaki Terajima,Etsuro Hatano,Yasuyuki Shimahara,Yoshio Yamaoka.??Results of hepatic resection for hepatocellular carcinoma invading major portal and/or hepatic veins(J)Surgical Oncology Clinics of North America . 2003 (1)
  • 3Llovet JM,Bustamante J,Castells A,et al.Natural history of untreated nonsurgical hepatocellular carcinoma: rationale for the design and evaluation of therapeutic trials. Hepatology . 1999
  • 4Jie Shi,Eric C. H. Lai,Nan Li,Wei-Xing Guo,Jie Xue,Wan-Yee Lau,Meng-Chao Wu,Shu-Qun Cheng.A new classification for hepatocellular carcinoma with portal vein tumor thrombus. Journal of Hepato-Biliary-Pancreatic Sciences . 2011
  • 5Xiao-Ping Chen MD, PhD, FACS,Fa-Zu Qiu MD, PhD,Zai-De Wu MD, PhD,Zhi-Wei Zhang MD, PhD,Zhi-Yong Huang MD, PhD,Yi-Fa Chen MD, PhD,Bi-Xiang Zhang MD, PhD,Song-Qing He MD, PhD,Wan-Guang Zhang MD, PhD.??Effects of Location and Extension of Portal Vein Tumor Thrombus on Long-Term Outcomes of Surgical Treatment for Hepatocellular Carcinoma(J)Annals of Surgical Oncology . 2006 (7)
  • 6Jie Shi,Eric C. H. Lai,Nan Li,Wei-Xing Guo,Jie Xue,Wan Yee Lau,Meng-Chao Wu,Shu-Qun Cheng.??Surgical Treatment of Hepatocellular Carcinoma with Portal Vein Tumor Thrombus(J)Annals of Surgical Oncology . 2010 (8)
  • 7Kenneth S. H. Chok,Tan To Cheung,See Ching Chan,Ronnie T. P. Poon,Sheung Tat Fan,Chung Mau Lo.??Surgical Outcomes in Hepatocellular Carcinoma Patients with Portal Vein Tumor Thrombosis(J)World Journal of Surgery . 2014 (2)

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