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Stricturing Crohn's disease-like colitis in a patient treated with belatacept

Stricturing Crohn's disease-like colitis in a patient treated with belatacept
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摘要 Cytotoxic T-lymphocyte-associated antigen 4(CTLA-4) modifying agents have been involved in the development of intestinal inflammation,especially therapeutic monoclonal antibodies directed against CTLA-4. Here we report the appearance of a severe stricturing Crohn's disease-like colitis in a patient with a kidney allograft who was treated with belatacept,a recombinant CTLA-4-Ig fusion protein. Cytotoxic T-lymphocyte-associated antigen 4(CTLA-4) modifying agents have been involved in the development of intestinal inflammation,especially therapeutic monoclonal antibodies directed against CTLA-4. Here we report the appearance of a severe stricturing Crohn's disease-like colitis in a patient with a kidney allograft who was treated with belatacept,a recombinant CTLA-4-Ig fusion protein.
出处 《World Journal of Gastroenterology》 SCIE CAS 2017年第48期8660-8665,共6页 世界胃肠病学杂志(英文版)
关键词 Crohn’s DISEASE COLITIS BELATACEPT HHV-6 INFLAMMATORY BOWEL DISEASE Crohn's disease Colitis Belatacept HHV-6 Inflammatory bowel disease
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