摘要
目的探讨复方黄甘颗粒对复发性生殖器疱疹(Recurrent genital herpes,RGH)血清干扰素-γ(Interferon-γ,IFN-γ)、白细胞介素-4(Interleukin-4,IL-4)水平的影响。方法将90例复发性生殖器疱疹患者按随机数字表法分为治疗组和对照组各45例,分别测定治疗前后血清IFN-γ、IL-4水平,治疗组服用复方黄甘颗粒(1包,冲服,2次/d),对照组服用泛昔洛韦片(0.25 g,口服,3次/d),30 d为1个疗程。结果治疗组治疗前后血清IFN-γ、IL-4水平差异有统计学意义(P<0.01),治疗后治疗组与对照组比较,差异具有统计学意义(P<0.01)。结论复方黄甘颗粒能明显提高RGH患者血清IFN-γ水平,降低IL-4水平。
Objective To invest compound Huanggan granule on recurrent genital herpes(RGH) serum levels of interferon(IFN)-γ and interleukin(IL)-4 in patients with recurrent genital herpes. Methods 90 patients with RGH patients were randomly divided into treatment group and control group. The treatment group was given compound Huanggan particles(a package, two times a day), and the control group was given Famciclovir tablets(0.25 g, three times a day), 30 days for a course. Serum levels of IFN-γ and IL-4 were measured before and after treatment. Results Serum levels of IFN-γ, IL-4 differences were statistically significant(P<0.01) in treatment group before and after treatment. The differences between treatment group and control group were statistically significant after treatment(P<0.01). Conclusion Serum levels of IFN-γ increase, serum levels of IL-4 drop in patients with RGH by taking compound Huanggan particles.
出处
《中国中西医结合皮肤性病学杂志》
CAS
2014年第5期286-288,共3页
Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine
基金
湖南省自然科学基金(11JJ5061)
