吸入粉雾剂给药装置浅析及其综合评价

Brief analysis and comprehensive evaluation of devices for dry powder inhalation

与大多数制剂不同,吸入粉雾剂的装置设计直接影响制剂性能和临床疗效。本文就吸入粉雾剂给药装置的分类、发展历程、患者使用及监管要求方面进行了综述。最后,结合处方工艺、质量研究和给药装置各方面,对吸入粉雾剂进行了综合评价。

Unlike most drug products,the design of the device can influence the performance and clinical efficacy of a dry powder inhaler drug product directly. In this review,we focus on the classification,development,patient use and regulatory requirements of the device. Furthermore,we made a briefly comprehensive evaluation on the formulation,quality attributes,device of dry powder inhaler drug products.