摘要
本文介绍了FDA批准的肿瘤免疫治疗中的免疫检查点抑制剂,并简述了免疫检查点抑制剂的心脏毒性,尤其是免疫相关的心肌炎的临床特征、可能发病机制及治疗和管理。
The immuno-checkpoint inhibitors approved by FDA in tumor immunotherapy were introduced in this paper.The cardiotoxicity of immuno-checkpoint inhibitors,especially the clinical features,possible pathogenesis,treatment and management of immuno-related myocarditis,was briefly described in this paper.
作者
徐伟仙
李海燕
XU Wei-xian;LI Hai-yan(Peking University Third Hospital,Beijing 100191,China)
出处
《中国新药杂志》
CAS
CSCD
北大核心
2019年第17期2095-2099,共5页
Chinese Journal of New Drugs
基金
国家“重大新药创制”科技重大专项资助项目(2017ZX09304012-014)
关键词
免疫检查点抑制剂
心脏毒性
心肌炎
肿瘤免疫治疗
immunocheckpoint inhibitors
cardiac toxicity
myocarditis
cancer immunotherapy