幽门螺杆菌治疗与咽喉反流性疾病的疗效分析

Therapeutic effect of helicobacter pylori on laryngopharyngeal reflux disease

目的幽门螺杆菌(Hp)治疗与咽喉反流性疾病疗效的分析。方法收取2017年10月~2018年8月,耳鼻喉门诊共收集80例14C尿素酶测试阳性且患有咽喉反流性疾病的患者,依照门诊就诊单双号次序分为对照组与观察组,每组40例。对照组行质子泵抑制剂、生活习惯的改变,观察组则在其基础上增加抗幽门螺杆菌治疗。对两组患者临床治疗效果进行对比。结果由本次临床研究可知,观察组的有效率优于对照组(P<0.05)。两组患者在治疗前,其临床量表比较差异无统计学意义,在治疗后均较之前有显著改善(P<0.05),且观察组在改善幅度上显著优于对照组(P<0.05)。结论对Hp感染治疗能够在一定程度上改善LPRD患者的临床症状,提高其临床治疗效果,其价值值得肯定。

Objective To analyze the therapeutic effect of helicobacter pylori(Hp)on laryngopharyngeal reflux disease.Methods A total of 80 patients with 14C urease positive and laryngopharyngeal reflux disease were collected from the otolaryngology clinic from October 2017 to August 2018.The control group was treated with proton pump inhibitors and lifestyle changes,while the observation group was treated with anti-helicobacter pylori therapy,proton pump inhibitors and lifestyle changes.The clinical effects of the two groups were compared.Results According to the results of this clinical study,the observation group(70.00%)was superior to the control group(90.00%)in terms of treatment efficiency(P<0.05).There was no statistically significant difference in clinical scales between the two groups before treatment.After treatment,there were significant improvements in both groups(P<0.05),and the improvement of the observation group was significantly better than that of the control group(P<0.05).Conclusion Hp treatment can improve the clinical symptoms of LPRD patients to a certain extent and improve the clinical treatment effect.