中药超声雾化口吸入治疗鼻咽癌放化疗后口干症临床观察

Clinical observation of inhalation of traditional Chinese medicine ultrasonic atomization mouth in the treatment of dry mouth syndrome after radiotherapy and chemotherapy for nasopharyngeal carcinoma

目的利用中医耳鼻喉科的外治特色疗法,对患者进行对症治疗,观察中药超声雾化口吸入治疗鼻咽癌放化疗后口干症临床疗效。方法观察2018年9月~2019年2月上海市天山中医医院耳鼻喉科门诊接诊鼻咽癌放化疗后出现干燥性鼻咽炎患者30例。年龄40~70岁,病程均为鼻咽癌放化疗结束后6个月至3年。应用自拟方药,通过中药超声雾化口咽吸入,治疗周期为每次20 min,每日1次,治疗5 d后间隔2d,总共治疗10次。治疗前后通过临床客观检查观察粘膜情况,口干症状情况评分结果,观察治疗效果。结果治疗前评分均为4分,治疗后评为3分2个,2分3个,1分2个,结果提示临床结果均为有效。结论中医辩证外治法治疗鼻咽癌放化疗后引起的口干症有确切的临床疗效。

Objective Using the external treatment of traditional Chinese medicine otolaryngology,symptomatic treatment of patients,observe the clinical efficacy of Chinese medicine ultrasonic atomization mouth inhalation treatment of xerostomic cancer after radiotherapy and chemotherapy.Methods From September 2018 to February 2019,30 patients with dry nasopharyngitis appeared after receiving radiotherapy and chemotherapy for nasopharyngeal carcinoma at the Otolaryngology Clinic of Shanghai Tianshan Traditional Chinese Medicine Hospital.The age ranged from 40 to 70 years,and the course of disease was 6 months to 3 years after the end of radiotherapy and chemotherapy for nasopharyngeal carcinoma.The self-prepared prescription was applied,and the oral pharyngeal inhalation was performed by ultrasonic atomization of traditional Chinese medicine.The treatment period was 20 min each time,once a day,and after 2 days of treatment,the interval was 2 days,and a total of 10 treatments were performed.Before and after treatment,the mucosal condition was observed by clinical objective examination,and the results of the dry mouth symptoms were evaluated to observe the therapeutic effect.Results The scores before treatment were 4 points.After treatment,the scores were 3 points,2 points,2 points,3 points,1 point and 2 points.The results showed that the clinical results were all effective.Conclusions The traditional Chinese medicine dialectical external treatment has a definite clinical effect on the treatment of dry mouth caused by radiotherapy and chemotherapy in nasopharyngeal carcinoma.