万应膏联合蒲地蓝消炎口服液辅助治疗流行性腮腺炎77例临床观察

Clinical observation on Wanying Gao (万应膏) combined with Pudilan Xiaoyan Koufuye (蒲地蓝消炎口服液) in adjunctive treatment of 77 cases with angina parotidea

目的观察万应膏外敷联合蒲地蓝消炎口服液内服辅助治疗小儿流行性腮腺炎的疗效。方法将150例流行性腮腺炎患儿随机分为2组,对照组给予西医常规治疗,治疗组在对照组治疗方法的基础上加万应膏外敷及蒲地蓝消炎口服液口服,治疗7 d后观察2组的临床疗效,主要症状消失时间,血清、尿淀粉酶的变化情况。结果治疗过程中共脱失病例17例,其中治疗组5例,对照组12例,最终有效病例治疗组77例,对照组56例。治疗组总有效率为97.4%,对照组为85.7%,2组比较,差异有统计学意义(P<0.05)。治疗组体温恢复正常时间、腮腺肿胀疼痛消失时间明显短于对照组,2组比较,差异有统计学意义(P<0.05)。2组治疗前血清淀粉酶、尿淀粉酶比较,差异均无统计学意义(P>0.05),具有可比性。治疗后2组血淀粉酶下降显著,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组下降更明显。治疗后2组尿淀粉酶比较,差异无统计学意义(P>0.05)。结论万应膏外敷联合蒲地蓝消炎口服液内服辅助治疗小儿流行性腮腺炎疗效显著,可快速有效减轻疼痛、缩短病程等特点,值得临床推广应用。

Objective To observe the clinical efficacy of Wanying Gao( 万应膏) for external application combined with Pudilan Xiaoyan Koufuye( 蒲地蓝消炎口服液) for oral administration in adjunctive treatment of children with angina parotidea.Methods Totally 150 children patients with angina parotidea were randomly divided into two groups,the control group was treated with routine Western medical therapy,while the treatment group was added with external application of Wanying Gao and oral administration of Pudilan Xiaoyan Koufuye based on treatment of the control group. The clinical efficacy,the disappearing time of cardinal symptoms and the change of amylase in serum and urine in the 2 groups were observed after 7 days of treatment.Results In the course of treatment,the missing cases were 17,including 5 cases of the treatment group and 12 cases of the control group.The final effective cases were 77 in the treatment group and 56 in the control group. The total effective rate of the treatment group was 97.4% and that of the control group was 85.7%,the difference was of statistical significance( P<0.05).Temperature recovery time,time of pain disappearance and swelling disappearance of treatment group was significantly shorter than those of control group,difference between the 2 groups had statistical significance( P< 0.05).There was no significant difference in serum amylase and urine amylase between the 2 groups before treatment( P>0.05),and they were comparable. Serum amylase of the 2 groups after treatment decreased significantly compared with the same group before treatment,the difference was of statistical significance( P < 0. 05),and the treatment group decreased more significantly. However,there was no significant difference in urine amylase between the 2groups after treatment( P>0.05).Conclusion External application of Wanying Gao combined with oral administration of Pudilan Xiaoyan Koufuye is very effective in adjunctive treatment of children with angina parotidea.It has the characteristics of reducing pain and shortening the course of disease quickly and effectively,which is worthy of clinical promotion and application.