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益肾健脑法治疗抑郁的现代科学机制 被引量:8

Modern Mechanism of Treating Depression by Tonifying Kidney and Strengthening Brain Method
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摘要 为了探讨益肾健脑法在治疗抑郁症中的相关研究和应用,通过抑郁症的发病机制以及其在临床和基础实验中的研究和应用进行总结。抑郁症的发病机制主要与神经营养因子的保护和再生,单胺类神经递质水平以及下丘脑-垂体-性腺轴的功能有关。近期研究表明,抑郁症的发病与海马神经元再生障碍密切相关,中医学益肾治疗可以保护神经元,促进神经元的分化和再生等。对益肾健脑法治疗抑郁症的作用机制进行了现代科学探讨,益肾可以通过调节中枢性激素水平或其受体功能状态来完成其健脑功能,达到防治抑郁的效果。 It explored the research and application of tonifying kidney and strengthening brain method in treatment of depression,conducting a summary of the pathogenesis of depression and its research and application in clinical and basic experiments.The mechanism mainly involves monoamine neurotransmitters,HPGA axis function and neurotrophic factor and nerve regeneration.The recent studies have shown that the incidence of depression is closely related to hippocampal neuronal dysplasia and tonifying kidney therapy can protect neurons and promote the neuron’s differentiation and regeneration.This article has carried on the modern scientific inquiry to the mechanism of treatment of depression by the method of tonifying kidney and strengthening brain therapy.Tonifying kidney therapy can regulate the central sex hormone levels orits receptor function to complete its brain function and achieve the effect of prevention and treatment of depression.
作者 邵帅 徐红丹 张博 黄树明 SHAO Shuai;XU Hongdan;ZHANG Bo;HUANG Shuming(Research Institute of Chinese Medcine,Heilongjiang University of Chinese Medcine,Harbin 150040,Heilongjiang,China)
出处 《中华中医药学刊》 CAS 北大核心 2019年第10期2332-2335,共4页 Chinese Archives of Traditional Chinese Medicine
基金 国家自然科学基金项目(81603321) 黑龙江省自然科学基金项目(H2016072) 黑龙江中医药大学博士创新基金项目(2015bs04)
关键词 抑郁症 益肾健脑 发病机制 depression tonifying kidney and strengthening brain pathogenesis
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