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基于“肝藏血主疏泄”理论探讨绝经后骨质疏松症的病因病机 被引量:17

Etiology and pathogenesis of postmenopausal osteoporosis based on the theory of "liver-blood-storing and controlling dispersion"
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摘要 绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)是中老年女性常见的全身性骨代谢疾病,严重影响着中老年女性的身心健康及生活质量。中医学认为随着年龄的增长,肝藏血功能减退,精血化生不足,其次中老年女性由于天癸衰竭易致肝气郁结、化火伤阴等,使肝的疏泄功能减退,最终致使精血亏虚或精血运行不畅,骨络失于濡养进而发生PMOP。众多医家多从肾、肝、脾及瘀血等方面探讨分析PMOP。本文基于文献的整理并结合中老年女性生理特性,从"肝藏血主疏泄"功能分析PMOP的病因病机及临床治疗效果,旨在为临床辩证治疗提供一定的参考,以期达到降低PMOP带来的严重并发症及提高中老年女性患者的生活质量。 Postmenopausal osteoporosis(PMOP)is a common systemic bone metabolic disease in middle-aged and elderly women,which seriously affects the physical and mental health and quality of life of middle-aged and elderly women.Chinese medicine believes that with the growth of age,liver and blood function decline,lack of blood and metaplasia,followed by middle-aged and elderly women due to the failure of congenital,prone to cause liver Qi stagnation,phlegm and other causes of liver dysfunction,eventually leading to blood loss virtual or refined blood runs poorly,and the bones fail to support and PMOP occurs.Many doctors have discussed the analysis of PMOP from the aspects of kidney,liver,spleen,and blood stasis.This article analyzes the etiology,pathogenesis,and clinical treatment of PMOP from the function of liver and blood storage,combining the physiological characteristics of middle-aged and elderly women.The aim is to provide a certain reference for clinical dialectical treatment in order to reduce the serious complications of PMOP and improve the quality of life of middle-aged and elderly women.
作者 李建国 谢兴文 李宁 徐世红 李鼎鹏 LI Jian-guo;XIE Xing-wen;LI Ning;XU Shi-hong;LI Ding-peng(Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China;Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,China;Gansu institute of Chinese medicine,Lanzhou 730050,China)
出处 《中国中医基础医学杂志》 CAS CSCD 北大核心 2019年第9期1203-1206,共4页 JOURNAL OF BASIC CHINESE MEDICINE
基金 国家自然科学基金资助项目(地区)(81860864) 兰州市科技局社会发展项目(2016-3-102) 甘肃省属科研院所基础条件建设专项(18JR2TA016) 国家中医药管理局中医临床研究基地业务建设专项(JDZX2015080) 甘肃省省级引导科技创新发展专项资金项目 甘肃省卫健委十三五重点专科培育项目
关键词 绝经后骨质疏松症 中医 肝脏 病因病机 疗效 Postmenopausal osteoporosis Traditional Chinese medicine Lirer Etiology and pathogenesis Curative effect
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