2011—2017年合肥地区孕妇及新生儿TORCH筛查结果

Results of TORCH screening in pregnant women and newborns in Hefei from 2011-2017

目的了解2011—2017年合肥地区年孕妇及新生儿血清TORCH-IgG阳性率,分析合肥地区孕妇及新生儿TORCH感染情况。方法采用ELISA对安徽医科大学第一附属医院就诊的2 267例合肥孕妇及2 614例新生儿血清进行TORCHIgG检测,分析2011—2017年孕妇及新生儿TORCH感染趋势;统计TORCH-IgG阳性率,并分析其与新生儿性别及孕妇年龄的相关性。结果 2011—2017年孕妇及新生儿血清TORCH-IgG阳性率呈现波动性,除巨细胞病毒(CMV)外,孕妇及新生儿其余4种TORCH-IgG阳性率变化趋势大体一致。在2 267例孕妇和2 614名新生儿中,TORCH-IgG阳性率最高的均为CMV-IgG,其次为HSV1-IgG,最低为TOX-IgG,TORCH-IgG阳性率在不同性别新生儿差异均无统计学意义(均P>0.05)。高龄孕妇HSV2-IgG阳性率明显高于低龄孕妇(χ2=12.462,P<0.05),其余TORCH-IgG与孕妇年龄无关(P>0.05)。结论合肥地区孕妇TORCH-IgG阳性率较高,既往感染率高,应早期进行TORCH筛查,并早期干预,减少孕妇感染率,提高人口质量,达到优生优育。

[Objective]To understand the positive rate of TORCH-IgG in serum of pregnant women and newborns in Hefei from2011-2017,and analyze the infection of TORCH in pregnant women and newborns.[Methods]ELISA was used to detect the serum of 2 267 Hefei pregnant women and 2 614 neonates in the First Affiliated Hospital of Anhui Medical University for TORCH-IgG detection,and the trend of TORCH infection in pregnant women and newborns from 2011-2017 was analyzed.The positive rate of TORCH-IgG was calculated and its correlation with the gender of newborn and the age of pregnant women was analyzed.[Results]From 2011-2017,the positive rate of serum TORCH-IgG of pregnant women and newborn children showed fluctuation.Except for cytomegalovirus(CMV),the positive rate of other 4 TORCH-IgG of pregnant women and newborn children showed the same trend.Among 2 267 pregnant women and 2 614 newborns,the highest positive rate of TORCH-IgG was CMVIgG,followed by HSV1-IgG,and the lowest was TOX-IgG.The positive rate of TORCH-IgG was not statistically significant among newborns of different genders(all P>0.05).The positive rate of HSV2-IgG in older pregnant women was significantly higher than that in younger pr egnant women(χ2=12.462,P<0.05),and the remaining TORCH-IgG had no relationship with maternal age(P>0.05).[Conclusion]TORCH-IgG positive rate of pregnant women in Hefei is relatively high,with a high infection rate in the past.Therefore,early TORCH screening and early intervention should be carried out to reduce the infection rate of pregnant women,improve the quality of population,and achieve the goals of optimal birth and breeding.