2017年贵阳市580例尘肺患者的肺弥散功能分析

Analysis of pulmonary dispersion function in 580 pneumoconiosis patients in Guiyang City in 2017

目的了解2017年贵阳市尘肺患者肺弥散功能的基本情况及不同期别的损伤程度,为肺弥散功能在职业健康监护中的应用提供基础资料,为临床医生诊断治疗、评价治疗效果和鉴定等提供参考依据。方法运用普查的方法选取2017年经贵阳市公共卫生救治中心确诊的尘肺病患者,收集患者进行肺功能检查的数据,对其肺弥散功能进行分析。结果 580例尘肺患者中尘肺壹期458例,贰期111例,叁期11例。不同尘肺期别之间年龄和接尘工龄比较,组间差异无统计学意义(P>0.05)。随着尘肺期别的不断上升,肺弥散功能的损伤程度不断加重(χ~2=13.303,P<0.05)。壹期、贰期和叁期尘肺的肺弥散功能异常率分别为23.8%、39.6%和72.7%,经χ~2检验差异有统计学意义(χ~2=6.683,P<0.05)。各期尘肺期别的一氧化碳弥散量(DLCO)实测值和DLCO实预比均有统计学意义(F=6.07、6.99,均P<0.01),各组间两两比较,在壹期和贰期、贰期和叁期、壹期和叁期组间差异均有统计学意义(均P<0.05)。结论 2017年贵阳市580例尘肺患者尘肺期别的不断上升,肺弥散功能的损伤程度不断加重;各期的肺弥散功能指标DLCO均值呈进行性下降;肺弥散功能的异常率增加。

[Objective]To understand the basic situation of pulmonary dispersion function and the degree of injury at different stages of pneumoconiosis patients in Guiyang City in 2017,to provide basic data for the application of pulmonary dispersion function in occupational health monitoring,and provide reference basis for clinicians to diagnose and treat,evaluate the treatment effect and identify.[Methods]The pneumoconiosis patients diagnosed by Guiyang Public Health Treatment Center in 2017 were selected by census method,and the data of pulmonary function examination were collected to analyze their pulmonary dispersion function.[Results]Among 580 patients with pneumoconiosis,there were 458 patients with stage 1,111 patients with stage 2 and 11 patients with stage 3.There was no significant difference in 2 age group and group of working age of dust exposure between patients with different pneumoconiosis stages(P>0.05).With the continuous increase of pneumoconiosis stage,the degree of damage to pulmonary dispersion function was aggravated(χ2=13.303,P<0.05).The rates of pneumoconiosis in the first,second and third phases were 23.8%,39.6%and 72.7%,respectively,and the difference was significant byχ2 test(χ2=6.683,P<0.05).The measured value of DLCO and DLCO actual pre-ratio were significantly different at all stages of pneumoconiosis(F=6.07,6.99,all P<0.01).There were statistically significant differences between the first and second,second and third,first and third groups(all P<0.05).[Conclusion]In 2017,580 cases of pneumoconiosis patients in Guiyang City had a continuous rise in pneumoconiosis stage,and the degree of damage to pulmonary dispersion function has been continuously aggravated.The DLCO average value of pulmonary dispersion function index in each stage shows a progressive decline.The abnormal rate of pulmonary dispersion function increased.