通瘀化浊汤加减联合中药直肠滴入治疗湿热瘀阻型Ⅱ～Ⅲ型慢性前列腺炎

Tongyu Huazhuo Decoction Combined with Traditional Chinese Medicine Instillation in the Treatment of Chronic Type Prostatitis Type Ⅱ-Ⅲ

目的分析通瘀化浊汤加减联合中药直肠滴入治疗湿热瘀阻型的Ⅱ～Ⅲ型慢性前列腺炎的临床疗效。方法选取湿热瘀阻型Ⅱ～Ⅲ型慢性前列腺炎患者180例,随机分为观察组和对照组,每组90例。对照组(Ⅱ、ⅢA)型患者接受左氧氟沙星胶囊进行治疗,ⅢB型患者接受盐酸特拉唑嗪胶囊治疗;观察组接受通瘀化浊汤加减联合中药直肠滴入的方法治疗。治疗4周后,对比分析2组患者的临床疗效、前列腺液白细胞变化等。结果治疗前2组NIH-CPSI评分比较,差异无统计学意义。治疗后,2组NIH-CPSI评分均明显下降(P <0.001),治疗后观察组NIH-CPSI评分明显低于对照组(P <0.001)。观察组总有效率为92.22%,明显高于对照组的68.89%(P <0.001)。治疗前2组前列腺白细胞水平比较,差异无统计学意义(P> 0.05),治疗后2组前列腺液白细胞水平明显下降,与治疗前相比,差异有统计学意义(P <0.001),治疗后观察组前列腺液白细胞水平明显低于对照组(P <0.001)。结论通瘀化浊汤加减联合中药直肠滴入治疗湿热瘀阻型慢性前列腺炎能促进病灶周围血液循环及炎症吸收。

Objective To investigate the clinical curative effect of Tongyu Huazhuo decoction combined with traditional Chinese medicine rectal infusion in the treatment of damp-heat stasis type II-III chronic prostatitis.Methods 180 cases of damp-heat stasis of type II-III chronic prostatitis were divided into observation group and control group, each group of 90 cases. Patients in the control group(type Ⅱ, Ⅲ A) were treated with levofloxacin capsules. Type Ⅲ B patients were treated with terazosin hydrochloride capsules. Patients in the observation group were received treatment with Tongyu Huazhuo decoction combined with traditional Chinese medicine rectal infusion.After four weeks, the clinical efficacy and changes of leukocytes in prostatic fluid were compared and analyzed between the two groups. Results Before treatment, the NIH-CPSI scores of the two groups were not significantly dif ferent. After treatment, NIH-CPSI scores in both groups were significantly decreased(P < 0.001). After treatment,the NIH-CPSI scores in the observation group were significantly lower than those in the control group(P < 0.001).The total effective rate of observation group was 92.22%, which was significantly higher than the control group(68.89%)(P < 0.001). Before treatment, there was no significant difference in the level of prostate leukocytes between the two groups(P > 0.05). After treatment, the leucocyte level of prostatic fluid in the two groups decreased significantly, and the dif ference was statistically significant compared with that before treatment(P < 0.001). After treatment, the levels of prostatic fluid leukocytes in the observation group were significantly lower than those in the control group(P < 0.001). Conclusions Tongyu Huazhuo decoction combined with rectum drip therapy can promote blood circulation and inflammatory absorption of damp-heat stagnation chronic prostatitis.