桃红四物汤对股骨远端骨折内固定术后愈合及膝关节功能的影响

Effect of Taohong Siwu Decoction in the Treatment of Patients After Internal Fixation of Distal Femoral Fractures on Knee Joint Function

目的探讨桃红四物汤加减对股骨远端骨折内固定术后愈合及膝关节功能的影响。方法选择我院行内固定术治疗的股骨远端骨折患者86例,随机分为2组,对照组采用加压钢板内固定术;观察组在此基础上采用桃红四物汤加减治疗,连续治疗4周。结果对照组有效率76.76%,低于观察组93.02%(P <0.05)。治疗后对照组和观察组VAS评分分别为(1.45±0.63)(0.78±0.52),HSS膝关节评分分别为(67.64±12.58)(77.31±10.24),血BALP分别为(27.89±7.57)μg/L、(35.81±8.24)μg/L,血β-CTX分别为(0.72±0.38)μg/L、(0.40±0.35)μg/L,上述指标比较差异具有统计学意义(P <0.05)。对照组骨折愈合时间(48.15±12.34)d高于观察组(35.62±10.45)d(P <0.05)。对照组并发症发生率11.63%与观察组9.30%比较,差异无统计学意义(P> 0.05)。结论桃红四物汤有助于促进股骨远端骨折内固定术后的愈合,改善膝关节功能,与BALP升高和β-CTX降低相关。

Objective To investigate the effect of decoction of Taohong Siwu decoction in the treatment of patients after internal fixation of distal femoral fractures on knee joint function.Methods 86 patients after internal fixation of distal femoral fractures were randomly divided into two groups,the control group received compression plate internal fixation,and the observation group received Taohong Siwu decoction,and two groups were treated for four weeks.Results The effective rate of the control group was 76.76%,which was lower than that of the observation group(93.02%)(P<0.05).The VAS scores of the control group and observation group were(1.45±0.63),(0.78±0.52),the HSS knee joint scores were(67.64±12.58),(77.31±10.24),the blood BALP were(27.89±7.57)μg/L,(35.81±8.24)μg/L,and the bloodβ-CTX were(0.72±0.38)μg/L,(0.40±0.35)μg/L,all indexes in two groups had statistically significant differences(P<0.05).The fracture healing time of the control group(48.15±12.34)d was higher than the observation group(35.6±10.45)d,and the difference was statistically significant(P<0.05).The complication rate in the control group 11.63%and 9.30%in the observation group had no differences(P>0.05).Conclusion Taohong Siwu decoction in the treatment of patients after internal fixation of distal femoral fractures was effective,and it can promote the healing of distal femoral fractures after internal fixation and improve knee function,which is related to the elevation of BALP and the decrease ofβ-CTX.