凉血祛湿止痒汤治疗急性湿疹临床观察

The Clinical Observation on the effects of Liang Xue Qushi Zhiyang Decoction on 72 Patients with Acute Eczema

目的观察凉血祛湿止痒汤治疗急性湿疹临床疗效。方法采用阳性药物随机对照研究方法 ,将144例急性湿疹患者随机分为治疗组和对照组各72例,治疗组口服凉血祛湿止痒汤,对照组口服氯雷他定片,疗程2周。结果对照组有效病例70例,脱落2例,治疗组有效病例71例,脱落1例;治疗组总有效率为85.92%,高于对照组的77.14%(P<0.05);治疗组在改善患者皮损的红斑、丘疹、水疱、渗出、面积、瘙痒症状以及中医证候等方面均优于对照组(P<0.01);治疗组复发率为3.23%,低于对照组的15.00%(P<0.01);两组在治疗过程中无不良反应发生。结论凉血祛湿止痒汤治疗急性湿疹临床疗效确切,复发率低。

Objective: To observe the clinical effects of Liang Xue Qushi Zhiyang Decoction on patients with acute Eczema. Methods: 144 cases of acute Eczema were randomly divided into treatment group with Liang Xue Qu Shi Zhi Yang Decoction(72 cases) and the control group with Loratadine tablet(72 cases). The course of treatment was two weeks. Results: 70 effective cases were completed,and unfinished cases were 2 cases in the control group,while 71 effective cases were done,and unfinished cases was 1 ones in the treatment group;After two weeks the total effective rates of the control group was 77.1%,the treatment group was 85.9%,the later was superior to the former by the Wilcoxon rank sum test(P < 0.05);The lesions(concluding erythema,papules,blisters,exudation,area,itching) in patients with acute eczema and patients′ TCM Syndrome were significantly improved in the treatment group,the effects were significantly better than the control group by t test(P < 0.01);Recurrence rate was 3.2% in the treatment group,which was less than one in the control group(15%,P < 0.01);There was no adverse events during treatment. Conclusions: Liang Xue Qu Shi Zhi Yang Decoction was effective on patients with acute eczema,and recurrence rate of acute eczema was relatively low.