复方南瓜藤软膏治疗疮疡阳证(未溃期)的临床研究

The Clinical Research of the Compound Vines Ointment on Ulcers of Yang Syndrome(not Collapse Period)

目的观察复方南瓜藤软膏外用治疗疮疡阳证(未溃期)的临床疗效。方法将65例患者按随机数字表法分为治疗组33例与对照组32例。治疗组和对照组又按疾病程度分为轻度组34例和中度组31例。轻度组34例患者分别使用复方南瓜藤软膏(治疗组)和鱼石脂软膏(对照组)外敷治疗。中度组31例患者,除了分别使用复方南瓜藤软膏和鱼石脂软膏外敷治疗外,同时均服用五味消毒饮。两组疗程均为2周。结果轻度组患者试验组17例,对照组17例。其中试验组痊愈病例17例,有效率100.00%;对照组痊愈病例17例,痊愈率100.00%。差异无统计学意义(P>0.05)。两组治疗天数比较,差异无统计学意义(P>0.05)。两组中度患者治愈率比较,治疗组中度患者16例,对照组中度患者15例。其中治疗组有效16例,有效率100.00%;对照组有效12例,有效率80.00%。两组中度患者治疗前,治疗后1、7、14 d后中度患者红肿范围比较,结果示治疗组在治疗后1、7、14 d均优于对照组(P<0.05)。结论对于轻度疮疡阳证患者,单独使用复方南瓜藤软膏外敷就可以治愈疾病,且其治愈天数较短。针对中度疮疡阳证(未溃期)患者,在服用中药治疗的同时,使用复方南瓜藤软膏外敷,其临床治疗有效率较高,且复方南瓜藤软膏对于患者临床红肿面积的消除和症状体征积分的改善具有明显的作用。

Objective: To observe the clinical effects of the compound vines ointment on ulcers of Yang syndrome(not collapse period). Methods: 65 cases with ulcers of Yang syndrome(not collapse period) were randomly divided into the treatment group(33 cases) and the control group(32 cases). According to the degree of disease,the treatment group and the control group were divided into the mild group of 34 cases and the moderate group of 31 cases. The mild group received the compound vines ointment(the treatment group) and ichthyol ointment topical treatment(the control group). The moderate group of 31 patients,in addition to using the compound vines ointment and ichthyol ointment topical treatment,took Wuwei xiaodu drink at the same time. The treatment course lasted for 2 weeks. Results: The mild group included 17 cases of the treatment group,and 17 cases of the control group. Both the treatment group and the control group had 17 cured cases,and the effective rate of both were100%;the difference was not statistically significant(P > 0.05). The fewest treatment days was 3 days and the most was 13 days in the treatment group,while the fewest treatment days was 4 days and the most was 12 days in the control group;the difference was statistically significant(P < 0.05). The moderate group included 16 cases of the treatment group,and 15 cases of the control group. In the treatment group,16 cases were effective,and the effective rate was 100%,while in the control group,12 cases were effective,and the effective rate was 80%. The difference was statistically significant(P < 0.05). Comparing the red range of the moderate patients before treatment and on 1st,7th,and14 th day after treatment,the treatment group was superior to the control group(P < 0.05).Conclusion: For mild patients with ulcers of Yang syndrome,external treatment of the compound vines ointment used alone can cure the disease,and its cure days is shorter. For moderate patients(not collapse period),Chinese traditional medicine treatment combined with external treatment of the compound vines ointment has a high efficient,and the compound vines ointment has obvious effect on clinical signs and symptoms and elimination of the red area,better than ichthyol ointment.