Attenuation of high glucose induced podocyte injury by ursolic acid up-regulating autophagy level

Objective To investigate the effects of ursolic acid(UA)on autophagy and podocyte injury induced by high glucose.Methods Conditionally immortalized murine podocytes were cultured in high glucose,the effect of PI3K inhibitor LY294002 and ursolic acid treatment were observed.The mi R-21 expression was detected using RT-