Impact of subclinical hypothyroidism on clinical outcome of patients coronary heart disease undergoing percutaneous coronary intervention

Objective To compare the clinical outcome of coronaryheart disease patients with normal TSH (ET) andsubclinical hypothyroidism ( SCH) after PCI. MethodsThis prospective cohort study analyzed the impact of differentlevels of thyroid stimulating hormone ( TSH) onclinical outcomes in patients with coronary heart diseasepost PCI. All the patients were divided into two groupswith normal thyroid function (ET group) and subclinicalhypothyroidism ( SCH group);SCH group was furtherdivided into: SCH group 1 (slightly elevated TSH level:4. 5 - 6. 9 mIU/L) and SCH group 2 (Intermediate elevationof TSH levels > 7. 0 mIU /L). Adverse clinicaloutcome includes: non-fatal myocardial infarction,revascularization,complex events, cardiogenic death afterPCI. The independent correlation between various thyroidhormone levels and adverse clinical outcomes wasassessed by multivariate Cox regression analysis.