摘要
Objective To analyze the clinical features and clinicalsignificance of patients with inflammatory bowel disease( IBD) complicated by thrombosis. Methods From March 14th,2001 to February sixth 2017,at NanjingGeneral Hospital of Nanjing Military Command,27 IBDpatients with thrombosis diagnosed by clinical symptoms,endoscopy,imaging and pathology were enrolled. Duringthe same period,81 gender and age matched IBD patientswithout thrombosis were included in the controlgroup. The basic data,information of IBD diagnosis andtreatment and thrombotic events of patients were collectedand analyzed. T-test and Chi-square test were performedfor statistical analysis. Binary logistics regression wasused for risk factors analysis. Results The mean age ofdiagnosis of IBD patients with thrombosis was (44. 8 ±15. 8) years,which was higher than that of IBD patientsof the control group ((36. 0 ± 14. 4) years),and thedifference was statistically significant ( t = 2. 69,P =0. 008). Among 27 IBD patients with thrombosis,arterialthrombosis was 51. 9% (14 /27),deep venous thrombosisof the lower extremity veins was 29. 6% (8 /27),portal venous system involved was 11. 1% (3 /27),pulmonaryembolism was 3. 7% (1 /27) and disseminatedintravascular coagulation accounted for 7. 4% (2 /27 ).Nine patients (33. 3%,9 /27 ) underwent surgery sixmonths before the diagnosis of thrombosis.
作者
李谨
LI Jin(Bengbu Med Coll,Bengbu 233003)