低分子肝素钠治疗慢性阻塞性肺疾病急性加重期患者的疗效观察

Effect of Low Molecular Weight Heparin Sodium in the Treatment of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

目的探讨低分子肝素钠在慢性阻塞性肺疾病急性加重期(AECOPD)患者中的应用。方法 66例AECOPD患者随机分为研究组与对照组。两组患者均予常规治疗,研究组患者加用低分子肝素钠5000 U皮下注射,每12小时1次,治疗10 d后复测患者动脉血气分析和肺功能。结果治疗后,研究组患者的动脉血气指标、肺功能明显优于对照组患者,差异有统计学意义(P<0.05)。结论 AECOPD患者经低分子肝素钠治疗的临床效果十分显著。

Objective To investigate the application of low molecular weight heparin sodium in patients with chronic obstructive pulmonary disease with acute exacerbation(AECOPD).Methods 66 patients with AECOPD were randomly divided into study group and control group.The two groups were treated with conventional therapy,the study group were treated with low molecular weight heparin sodium 5000 U,12 d,H 1 times,and the arterial blood gas analysis and pulmonary function were measured in 10 patients.Results After treatment,the arterial blood gas and pulmonary function of the study group were significantly better than those of the control group,the difference was statistically significant(P<0.05).Conclusion The clinical effect of low molecular weight heparin sodium for treatment of patients with AECOPD is very significant.