医院药房抗生素使用情况分析

Analysis of the use of antibiotics in hospital pharmacy

目的通过分析我院药房抗生素使用情况,提高抗生素用药的准确合理性。方法收集2015年1月至2016年3月于泰州市第二人民医院行非手术治疗的270患者的临床资料,调查分析包括抗生素使用种类、品种数、用药剂量、疗程、病原学送检情况等,计算患者抗菌药物使用率、使用抗生素治疗患者的病原学检测率、患者人均使用抗生素品种数、限定日剂量(DDD)、用药频度(DDDs)、使用强度(AUD)、平均用药时间等。结果我院住院药房抗生素使用率为57.9%,抗菌药物AUD平均为70(DDD/100人/d),治疗性使用抗菌药物住院患者病原学送检测率为41.9%;抗菌药物种类主要为头孢菌素类、喹诺酮类、青霉素类;头孢菌素类药物销售金额最高。结论医院抗菌药物使用率仍然较高,病原学检测率较低,抗生素种类选择较为集中,还需进一步对抗生素的应用进行管理。

Objective to analyze the use of antibiotics in our hospital pharmacy, so as to improve the accuracy and rationality of clinical antibiotics.Methods From January 2015 to March 2016 in Taizhou Second People’s Hospital for non clinical data of surgical treatment of 270 patients,including the investigation and analysis of species,varieties of antibiotics use number,dosage,treatment and pathogenic detection etc,were calculated from the usage rate of antibacterial drugs,use of antibiotics in the treatment of patients with pathogen detection rate,with the use of antibiotics,the number of varieties defined per capita daily dose(DDD),frequency of drug use(DDDs),strength(AUD), the average medication time.Results The usage rate of antibiotics in our hospital 57.9% inpatient pharmacy,antibiotic AUD averaged 70(DDD/100/d),the therapeutic use of antibacterial,send detection rate of 41.9% hospitalized patients with pathogenic agents;antibacterial drug types mainly include cephalosporins,quinolones,penicillins,cephalosporins; the highest amount of sales.Conclusion Hospital antimicrobial drug use rate is still high,pathogenic detection rate is low, the choice of antibiotics is more concentrated,it is necessary to further the application of antibiotics for management.