双氯芬酸钠缓释片联合腰痛宁胶囊治疗腰椎间盘突出症术后下腰痛的临床观察

Clinical Observation on Diclofenac Sodium Sustained-release Tablets Combined with Yaotongning Capsules(腰痛宁胶囊) in the Treatment of Lower Back Pain after Operation for Lumbar Intervertebral Disc Prolapse

目的探讨双氯芬酸钠缓释片联合腰痛宁胶囊治疗腰椎间盘突出症患者术后下腰痛的临床疗效。方法选取2014年8月至2018年8月沈阳友谊美容医院外科收治的腰椎间盘突出症术后下腰痛患者60例作为研究对象,按照住院病历号将患者随机分为对照组和观察组,每组30例。对照组患者口服双氯芬酸钠缓释片以抗炎、镇痛对症治疗;观察组患者在对照组的基础上口服腰痛宁胶囊进行治疗,10 d为1个疗程,共治疗4个疗程。比较两组患者治疗前后的下腰痛评分(JOA)、视觉模拟评分(VAS)、下腰痛的功能障碍指数(ODI)及腰椎功能评价(MacNab)等指标的水平变化。结果两组患者治疗前的JOA、VAS、ODI差异无统计学意义(P>0.05);治疗后,两组患者的JOA、VAS及ODI评分均有所改善,且观察组优于对照组,差异均有统计学意义(均P<0.05);疗程结束后,对照组和观察组的优良率分别为43.3%和80.0%,两组比较,差异有统计学意义(P<0.05)。结论中西医结合治疗腰椎间盘突出症术后下腰痛的临床疗效优于单纯西药组,能够较好地缓解患者的疼痛,有效改善患者的生活质量。

Objective To investigate the clinical efficacy of diclofenac sodium sustained-release tablets combined with Yaotongning Capsules(腰痛宁胶囊) in the treatment of postoperative lower back pain in patients with lumbar intervertebral disc prolapse. Methods From August 2014 to August 2018, a total of 60 patients with lower back pain after operation for lumbar intervertebral disc prolapse enrolled in Department of Surgery of Shenyang Friendship Beauty Hospital were selected. Patients were randomly divided into control group and observation group according to hospitalization medical record number, with 30 patients in each group. The control group was given oral diclofenac sodium sustained-release tablets for symptomatic treatment of antiinflammatory and analgesic. The observation group was treated with Yaotongning Capsules on the basis of the control group for 4 10-day courses. The levels of low back pain score(JOA), visual analog scale(VAS), low back pain dysfunction index(ODI), and lumbar function evaluation(Mac Nab) were compared before and after treatment. Results There was no significant difference in scores of JOA, VAS and ODI between the two groups before treatment(P>0.05). After treatment, the JOA, VAS, and ODI scores of the two groups were improved. The observation group was superior to the control group, and the difference was statistically significant(P<0.05). After the end of the treatment period, the excellent and good rates of the control group and the observation group were 43.3% and 80.0%, respectively. The difference was statistically significant(P<0.05). Conclusion The clinical efficacy of integrated traditional Chinese and Western medicine in the treatment of low back pain after operation for lumbar intervertebral disc prolapse is better than that of Western medicine alone, and it can better alleviate the pain of patients and improve the quality of life.