地塞米松对腹腔镜阑尾切除术患者术后不良反应収生及肠平滑肌收缩的影响

The Influence of Dexamethasone on Adverse Reaction and Contraction of Intestinal Smooth Muscle after Laparoscopic Appendectomy

目的探讨地塞米松对腹腔镜阑尾切除术患者术后不良反应发生及肠平滑肌收缩的影响。方法选取2018年1—12月于揭阳产业转移工业园人民医院行腹腔镜阑尾切除术的80例患者作为研究对象,随机分为两组,对照组患者术后给予常规处理,观察组患者术后在对照组基础上通过静脉一次性注射地塞米松10 mg。比较两组患者术后康复情况。结果观察组患者术后1 h、6 h、12 h、24 h的视觉模拟评分法(VAS)评分均低于对照组(均P<0.05);观察组患者术后不良反应发生率低于对照组(P<0.05);治疗前两组患者三磷酸肌醇和游离钙离子水平比较差异均无统计学意义(均P>0.05),治疗后观察组患者的三磷酸肌醇和游离钙离子水平均低于对照组(均P<0.05)。结论对腹腔镜阑尾切除术患者术后应用地塞米松,可降低不良反应发生率,使胃肠道功能快速恢复。

Objective To discuss on the effecacy of dexamethasone on the occurrence of adverse reactions and contraction of intestinal smooth muscle after laparoscopic appendectomy. Methods a total of 80 patients who underwent laparoscopic appendectomy in People’s Hospital of Jieyang Industrial Transfer Park from January to December 2018, were randomly divided into two groups. The patients in the control group were given routine treatment after operation while the patients in the observation group were injected with 10 mg dexamethasone intravenously after operation on the basis of the control group. Result VAS of the observation group, 1 hour, 6 hours, 12 hours and 24 hours after operation was lower than the control group(P<0.05). The rate of adverse reactions in the observation group was lower than that in the control group(P<0.05). There was no statistical difference in creatine triphosphate and free calcium ions between the two groups before treatment(P>0.05), and both creatine triphosphate and free calcium ions in the observation group were lower than those in the control group after treatment(P<0.05). Conclusion The application of dexamethasone after laparoscopic appendectomy can reduce the rate of adverse reactions and quickly restore gastrointestinal function.