耳穴贴压联合氟哌噻吨美利曲辛片治疗胃肠神经症的疗效观察

Observation on the Efficacy of Auricular Acupoint Sticking Combined with Flupentixol and Melitracen Tablets in the Treatment of Gastrointestinal Neurosis

目的探讨耳穴贴压联合氟哌噻吨美利曲辛片治疗胃肠神经症患者的临床疗效和安全性。方法将2017年12月至2018年12月于梅州市中医医院就诊的64例胃肠神经症患者作为研究对象随机分为对照组和观察组,每组32例。对照组患者仅给予氟哌噻吨美利曲辛片治疗,观察组患者给予耳穴贴压联合氟哌噻吨美利曲辛片治疗。比较两组患者临床疗效、不良反应发生情况及心理状态改善情况。结果治疗前,两组患者焦虑自评量表(SAS)和抑郁自评量表(SDS)评分比较差异均无统计意义学(均P>0.05);治疗2周、4周后,两组患者SAS评分、SDS评分均明显降低,且观察组下降幅度均优于对照组,差异均有统计学意义(均P<0.05);治疗4周后,观察组患者的总有效率为96.86%,显著高于对照组的81.25%(P<0.05);治疗期间观察组患者总不良反应发生率为6.25%,显著低于对照组的21.88%(P<0.05)。结论耳穴贴压联合氟哌噻吨美利曲辛片治疗胃肠神经症临床疗效显著,可有效改善患者焦虑抑郁情况,且更安全。

Objective To explore the clinical efficacy and safety of auricular acupoint sticking combined with flupentixol and melitracen tablets in the treatment of gastrointestinal neurosis.Methods A total of 64 patients with gastrointestinal neurosis who were treated in Meizhou Hospital of Traditional Chinese Medicine from December 2017 to December 2018 were randomly divided into control group and observation group,32 cases in each group.The control group was only treated with flupentixol and melitracen tablets,while the observation group was treated with auricular acupoint sticking combined with flupentixol and melitracen tablets.The clinical efficacy,adverse reactions and psychological improvement of the two groups were compared.Results Before treatment,there was no significant difference in SAS and SDS scores between the two groups(P>0.05);After 2 and 4 weeks of treatment,SAS scores and SDS scores of the 2 groups were significantly reduced,and the decrease range of the observation group was better than that of the control group,the difference was statistically significant(P<0.05);after 4 weeks of treatment,the total effective rate of the observation group was significantly lower than that of the control group(P<0.05).96.86%,significantly higher than 81.25%of the control group(P<0.05);the total incidence of adverse reactions in the observation group was 6.25%,significantly lower than 21.88%of the control group(P<0.05).Conclusion Auricular acupoint sticking combined with flupentixol and melitracen tablets in the treatment of gastrointestinal neurosis has significant clinical efficacy,can effectively improve the anxiety and depression of patients,and is safer.