中西医结合治疗慢性荨麻疹的疗效

Therapeutic Effects of Integrated Traditional Chinese and Western Medicine on Chronic Urticaria

目的探讨中西医结合治疗慢性荨麻疹的疗效和安全性。方法选取2017年5月至2018年5月阳江市公共卫生医院皮肤科收治的120例慢性荨麻疹患者作为研究对象,按照随机分配原则将其分为观察组(60例)和对照组(60例)。对照组单纯给予常规西药治疗,观察组在对照组基础上采用中药自拟方剂进行治疗,比较两组患者的治疗效果。结果观察组治疗有效率显著高于对照组(88.3%比70.0%,χ~2=6.1137,P<0.05),治疗后随访6个月,观察组复发率显著低于对照组(8.3%比41.7%,χ~2=17.7778,P<0.05)。两组患者治疗后皮肤病生活质量指数(DLQI)评分均低于治疗前,且观察组DLQI评分低于对照组,差异均有统计学意义(均P<0.05)。两组患者治疗期间不良反应发生率比较差异无统计学意义(P>0.05)。结论中西医结合疗法治疗慢性荨麻疹,较常规西药而言具有疗效突出、复发率低的优势,且安全性较高。

Objective To explore the efficacy and safety of integrated traditional Chinese and western medicine in the treatment of chronic urticaria.Methods A total of 120 patients with chronic urticaria admitted to dermatology department of Yangjiang public health hospital from May 2017 to May 2018 were selected as subjects,according to the principle of random distribution.And they were divided into an observation group(60 cases)and a control group(60 cases).The control group was treated with conventional western medicine alone,while the observation group was treated with traditional Chinese medicine self-made prescription on the basis of the control group,and then the therapeutic effects of the two groups were compared.Results The total effective rate of the observation group was significantly higher than that of the control group(88.3%vs.70.0%,χ~2=6.1137,P<0.05),following up for 6 months after treatment.The recurrence rate of the observation group was significantly lower than that of the control group(8.3%vs.41.7%,χ~2=17.7778,P<0.05).The dermatological quality of life index(DLQI)score after treatment in the two groups was lower than that in the control group,and the DLQI score in the observation group was lower than that in the control group.The difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups during treatment(P>0.05).Conclusion Compared with conventional western medicine,treatment of chronic urticaria with integrated of traditional Chinese and western medicine has the advantages of outstanding curative effects and low recurrence rate,and is highly safe.